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Last update: Martínek Karel, RNDr., Ph.D. (26.01.2021)
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Credit- winter semester: attendance on seminars with active participation - maximum of three absences tolerated, credit test at the end of the semester, resits during the winter exam period Credit- summer semester: attendance on seminars with active participation - maximum of three absences tolerated, credit test at the end of the semester, resits during the summer exam period Important notice: it is necessary to obtain credit from the winter semester before the beginning of the summer semester (by the end of the winter exam period). Dates for repeated credit tests will be available until the end of the winter exam period and will be listed in SIS. Credit can no longer be taken during the summer semester. Without both credits - from the winter semester and the summer semester, it is not permitid do the exam at the end of the summer semester. Last update: Martínek Karel, RNDr., Ph.D. (30.09.2024)
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7th edition (2013) available online https://ebookcentral.proquest.com/lib/cuni/detail.action?docID=1430832 - Murray PR: Basic Medical microbiology, Elsevier 2017 https://ebookcentral.proquest.com/lib/cuni/detail.action?docID=4810876 - (login by your CAS - UK account) Last update: Martínek Karel, RNDr., Ph.D. (05.10.2022)
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- Last update: Martínek Karel, RNDr., Ph.D. (26.01.2021)
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Microbiology - General Medicine, 2nd year Winter semester Seminars, 3 hrs/week
1. Introduction, history of clinical microbiology, evolution of microbes, general microbiology (viruses, bacteria, parasites, mechanism of parasitism and interaction between pathogen and host, pathogenicity, virulence – definitions, basic principles of immunity) 2. Phases of diagnostic process (pre-analytical phase - indication of laboratory examination, collection of clinical specimen and its transport to the laboratory, analytical phase, interpretation – post-analytical phase, laboratory handbook, request form, direct/indirect detection of pathogens) 3. Microscopy diagnostic methods (Gram stain, Ziehl-Neelsen stain, other staining methods, microscopy in bacteriology, mycology and parasitology, interpretation and evaluation) 4. Cultivation diagnostic methods (culture media, growth characteristics, identification of microbes, cultivation of viruses, special cultivation techniques) 5. Immunological and molecular genetic methods (principles of immunology methods, categories of antibodies, main laboratory assays, polymerase chain reaction - principles and options, sequencing, other methods) 6. Antibiotic therapy (determination of susceptibility to antibiotics, types of antibiotics, resistance to antibiotics, antibiotic stewardship) 7. Review of clinically important Gram-positive cocci (characteristics, factors responsible for virulence, diseases, diagnostics, epidemiology, antibiotic therapy; Streptococcus spp., Enterococcus spp., Staphylococcus spp., etc.) 8. Review of clinically important Gram-positive rods and anaerobes (characteristics, factors responsible for virulence, diseases, diagnostics, epidemiology, antibiotic therapy Bacillus spp., Corynebacterium spp., Clostridium ssp. Bacteroides ssp., Peptostreptococcus spp., Fusobacterium spp., etc.) 9. Review of clinically important Gram-negative bacteria (characteristics, factors responsible for virulence, diseases, diagnostics, epidemiology, antibiotic therapy; Neisseria spp., Haemophilus spp., Enterobacterales, Vibrio spp., Campylobacter spp., Helicobacter spp., Pseudomonas and other non-fermenting rods, Legionella spp.) 10. Review of clinically important bacteria - other (characteristics, factors responsible for virulence, diseases, diagnostics, epidemiology, antibiotic therapy; Mycobacterium spp., Nocardia spp., Actinomyces spp., Chlamydia spp., Mycoplasma spp., Rickettsia spp., etc.) 11. Review of clinically important fungi (characteristics, factors responsible for virulence, diseases, diagnostics, epidemiology, therapy; Candida spp., Cryptococcus spp., Aspergillus spp., dermatomycoses, Histoplasma spp., Pneumocystis jirovecii, etc.) 12. Review of clinically important parasites (taxonomy, life cycles, vectors, diseases, diagnostics, therapy; protozoa, helminths, parasitic arthropodes, review of the most important species- - Trypanosoma spp., Leishmania spp., Trichomonas vaginalis, Giardia intestinalis, Entamoeba histolytica, Plasmodium spp., Toxoplasma gondii, Taenia spp., Enterobius vermicularis) 13. Credits
Last update: Martínek Karel, RNDr., Ph.D. (30.09.2022)
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course Moodle Last update: Martínek Karel, RNDr., Ph.D. (07.02.2022)
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Credit- winter semester: attendance on seminars with active participation - maximum of three absences tolerated, credit test at the end of the semester, resits during the winter exam period Credit- summer semester: attendance on seminars with active participation - maximum of three absences tolerated, credit test at the end of the semester, resits during the summer exam period Important notice: it is necessary to obtain credit from the winter semester before the beginning of the summer semester (by the end of the winter exam period). Dates for repeated credit tests will be available until the end of the winter exam period and will be listed in SIS. Credit can no longer be taken during the summer semester. Without both credits - from the winter semester and the summer semester, it is not permitid do the exam at the end of the summer semester. Last update: Martínek Karel, RNDr., Ph.D. (30.09.2024)
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