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Last update: doc. MUDr. Jan Cendelín, Ph.D. (26.09.2023)
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (26.09.2023)
For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (see study literature). Students, who did not attend the class in time, will be not admitted to the class with the sanction of absence.
Prerequisites are knowledge from the fields to which the subject pathological physiology follows, i.e. anatomy, histology, embryology, biology, genetics, chemistry and biochemistry, biophysics, physiology and microbiology. |
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (08.02.2024)
Conditions for the credit – pathological physiology I:
1. Active attending practical exercises – 2 absences per semester are allowed. For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (see study literature). Prerequisites are knowledge from the fields to which the subject pathological physiology I follows, i.e. anatomy, histology, embryology, biology, genetics, chemistry and biochemistry, biophysics, physiology and microbiology. Students, who did not attend the class in time, will be not admitted to the class.
2. Submitting of correctly elaborated protocols of all experiments and practical exercises to the teacher, who assesses their correctness and confirms them as fulfilled, or returns them for revision.
The conditions of the credits for students having an individual study plan, who enrolled pathological physiology II for the second time, will be appointed individually in dependence on study duties passed in the previous academic year. These conditions will not exceed the range of above specified general duties. These students are required to contact the teacher of the relevant study group at the beginning of the semester.
Note: Pathological physiology I is followed by pathological physiology II completed with a credit and exam and the content of which also covers the knowledge from the pathological physiology I course in its entirety. |
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (26.09.2023)
Mandatory literature: Sobotka et al.: Pathophysiology – Laboratory Exercises. 2013, Karolinum, 2013 McPhee, Hammer et al.: Pathophysiology of Disease: An Introduction to Clinical Medicine. The McGraw-Hill Companies, Inc., 6th Edition 2010 (or later issues) Educational materials of the Department of Pathophysiology published on educational portals of the Faculty of Medicine in Pilsen, Charles University or the webpage of the department or provided to students in printed or electronic form.
Recommended literature: Hueher et al.: Understanding Pathophysiology. Elsevier, 2017 McCance and Huether: Pathophysiology, the Biologic Basis for Disease in Adults and Children. Elsevier, 2019 Banasik and Copstead: Pathophysiology. Elsevier, 2019 Hulín et al.: Pathophysiology. Slovak Academic Press, 1997 (or later issues) Silbernagl and Lang: Color Atlas of Pathophysiology. 3rd edition, Georg Thieme Verlag KG, 2016 Price and Wilson et al.: Pathophysiology – Clinical concepts of disease processes. Mosby, Inc., 2003 Guyton: Human physiology and mechanisms of disease. W. B. Saunders Company, the latest issue |
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (26.01.2024)
Pathological physiology I is followed by pathological physiology II that is completed with a credit and an exam.
Conditions for the pathological physiology II exam: The condition for registration for the exam is to obtain a credit in pathological physiology I and pathological physiology II, if not set differently for a specific term. The student is obliged to register for the exam before the deadline using SIS (other ways of registration will not be accepted). Registration is necessary for the regular term as well as for potential 1st re-examination or 2nd re-examination.
The required knowledge contains curriculum of both subjects pathological physiology I and pathological physiology II. Knowledge of other subjects to which pathological physiology follows is also necessary (see syllabus).
The exam consists of a practical exam and oral exam. The required knowledge is based on the list of exam questions and the syllabus of the subjects pathological physiology I and pathological physiology II (for detailed syllabus and list of questions for the practical exam and oral exam see webpage of the Department of Pathophysiology: http://patofyziologie.lfp.cuni.cz/?lang=en
Practical exam consists of 1 question and ECG record analysis. Failure in the practical exam means classification of the exam “fail”.
Oral exam consists of 4 questions. To pass the oral exam, the student must show sufficient knowledge in each of these 4 questions.
Final classification takes into consideration not only the performance in the oral exam but also the classification of the practical exam.
Practical and oral exams constitute one complex and cannot be separated into two examination terms. In the case of classification of any part of the exam "failed", the student is subjected to both the practical and oral exam again in the 1st or 2nd reexamination.
Due to capacity reasons, the exam can be divided into several days within the given exam date. Students are required to attend the appropriate stage of the exam according to the schedule or examiner's instructions. See also goals of teaching: |
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (26.09.2023)
Pathological physiology I: Syllabus of the subject - General medicine Individual topics can be moved between the subjects pathological physiology I and pathological physiology II.
General pathophysiology I Introduction to the subject, basic terms, disease and its course Etiological factors Classification of etiological and risk factors, particular intrinsic and extrinsic etiological factors Pathophysiology of wound healing Developmental disorders Causes and mechanisms of developmental disorders, diseases linked to a certain age Gametopathy, blastopathy, embryopathy, fetopathy, perinatal damage Growth disorders Aging, terminal states, death of an individual, cell death Pathophysiology of immunity Immunodeficiency, allergy, autoimmune diseases, inflammation, transplantation Pathophysiology of thermoregulation, fever Pathophysiology of tumors Special pathophysiology I Pathophysiology of the lymphatic system Pathophysiology of the blood Changes of blood volume and composition Disorders of erythrocytes, anemia, polycythemia, polyglobulia, hemolysis Pathophysiology of leukocytes – changes of number, disorders of function, leukemias Bleeding, hemorrhagic diathesis, thrombotic states Pathophysiology of the cardiovascular system Inborn and acquired heart defects Disturbances of peripheral blood circulation, atherosclerosis, endothelial dysfunction Ischemic heart disease, arrhythmias, arterial hypertension, thromboembolic disease Cardiac insufficiency and failure, circulatory shock Heart hypertrophy and dilatation, cardiomyopathy, heart inflammations Multiorgan dysfunction and multiorgan failure Pathophysiology of the endocrine system General causes of diseases of the endocrine glands, mechanisms of endocrine disorders Pathophysiology of individual endocrine structures and hormones Pathophysiology of the reproductive system Pathophysiology of the bones Pathophysiology of the muscles Manifestations of diseases of the skeletal muscles and their innervation Myopathies, muscular dystrophias, myositis, rhabdomyolysis, crush syndrome, compartment syndrome, malignant hyperthermia Acid-base balance and its disorders Pathophysiology of body fluids Pathophysiology of mineral metabolism Pathophysiology of the gastrointestinal tract Pathophysiology of the oral cavity, esophagus, stomach, gut, exocrine pancreas Dysphagia, nausea, vomiting, dyspepsia, constipation, diarrhea, gastrointestinal tract bleeding Practical knowledge and skills I Principles of science, statistics, injection technique, anesthesia, pathophysiological aspects of wound treatment, use of electricity in medicine, electrocardiography, blood pressure measurement, examination of hemorrhagic diatheses
Detailed syllabus for pathological physiolopgy I and subsequent subject pathological physiology II: |
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Last update: doc. MUDr. Jan Cendelín, Ph.D. (08.02.2024)
Conditions for the credit – pathological physiology I:
1. Active attending practical exercises – 2 absences per semester are allowed. For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (see study literature). Prerequisites are knowledge from the fields to which the subject pathological physiology I follows, i.e. anatomy, histology, embryology, biology, genetics, chemistry and biochemistry, biophysics, physiology and microbiology. Students, who did not attend the class in time, will be not admitted to the class.
2. Submitting of correctly elaborated protocols of all experiments and practical exercises to the teacher, who assesses their correctness and confirms them as fulfilled, or returns them for revision.
The conditions of the credits for students having an individual study plan, who enrolled pathological physiology II for the second time, will be appointed individually in dependence on study duties passed in the previous academic year. These conditions will not exceed the range of above specified general duties. These students are required to contact the teacher of the relevant study group at the beginning of the semester.
Note: Pathological physiology I is followed by pathological physiology II completed with a credit and exam and the content of which also covers the knowledge from the pathological physiology I course in its entirety. |