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Course, academic year 2023/2024
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Histology and Embryology II. - EAP0102040
Title: Histology and Embryology II.
Guaranteed by: Ústav histologie a embryologie (14-40)
Faculty: Faculty of Medicine in Pilsen
Actual: from 2021
Semester: winter
Points: 6
E-Credits: 6
Examination process: winter s.:
Hours per week, examination: winter s.:2/3, C+Ex [HT]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
For type:  
Note: deregister from the exam date if a requisite was not fulfilled
for a repeated registration for Course credit + Exam, the student must have the Course credit exam passed
Guarantor: prof. MUDr. Mgr. Zbyněk Tonar, Ph.D.
prof. MUDr. Milena Králíčková, Ph.D.
MUDr. Věra Křížková, Ph.D.
Teacher(s): Mgr. Yaroslav Kolinko, Ph.D.
prof. MUDr. Milena Králíčková, Ph.D.
MUDr. Věra Křížková, Ph.D.
doc. Ing. Jan Nevoral, Ph.D.
Ing. et Ing. Jiří Polívka, Ph.D.
prof. MUDr. Mgr. Zbyněk Tonar, Ph.D.
Attributes: Povinné předměty pro Všeobecné lékařství
Incompatibility : EA0103012
Pre-requisite : EAP0101030, EAP0101040
Interchangeability : EA0103012
Is interchangeable with: EA0103012
Annotation -
The student is gradually acquainted with the histological structure of all organ systems and can practically work with the microscope to identify, describe and understand microstructure of individual organs.
The student will learn about the development of a human being from the beginning (gamets and fertilization) to the birth. The student will understand the development of individual organs and organ systems and understand the most common malformations.
Last update: Jiráková Lucie, Bc. (25.10.2022)
Learning outcomes -

Learning goals and outcomes for subject Histology and embryology II : 

Learning-objectives-for-2nd-year-Histology.pdf (cuni.cz)

Last update: Merhautová Šárka (12.06.2024)
Course completion requirements -

The conditions for completing the course are described in the document Histology credit exam and Histology and Embryology II final exam rules in the academic year 2023/24 (see above).

Last update: Jiráková Lucie, Bc. (15.09.2023)
Literature -
    • Slípka J., Tonar Z.: Outlines of Histology. Karolinum, Prague, 2017.

    • Slípka J., Tonar Z.: Outlines of Embryology. Karolinum, Prague, 2019.

    • Balko J., Tonar Z., Varga I. et al.: Memorix Histology. Triton, Prague, 2018.

    • Mescher A.L.: Junqueira’s Basic Histology. Text & Atlas. 16th edition. McGrawHill, New York, 2021.

    • Sadler T.: Langman´s Medical Embryology, 15th edition, Wolters Kluwer 2023.
Last update: Jiráková Lucie, Bc. (14.11.2023)
Requirements to the exam - Czech

Podmínky získání zápočtu za zimní semestr:
1. Účast na praktických cvičeních - povoleny jsou 2 absence za semestr
2. Úspěšné absolvování zápočtových testů
3. Popis neoznačených preparátů

Podmínky úspěšného absolvování zkoušky:
1. Úspěšné absolvování testu v počítačové učebně 
2. Písemná část - správné nakreslení a popsání čtyř schémat - dvou z obecné histologie a dvou z embryologie
3. Úspěšná identifikace tří preparátů s pomocí mikroskopu
4. Ústní část zkoušky - tři teoretické otázky - jedna z obecné histologie, jedna z mikroskopické anatomie a jedna z embryologie

Last update: Jiráková Lucie, Bc. (25.10.2022)
Syllabus -

 Summary of the lectures - Embryology - Course: Embryology (cuni.cz):

1. INTRODUCTION: Embryological terms. The ethical problems of Embryology. History of embryology. Blastogenesis. Fertilization and differentiation. Cleavage.

2. BLASTOGENESIS and GASTRULATION: Blastocyst, Implantation, Gastrulation. Origin of the first Germ layers. Notogenesis (development of notochord). The embryonic disc and its development. Mesoderm and development of somites. Mesenchyme.

3. FETAL MEMBRANES AND PLACENTA DEVELOPMENT: Amniotic sac expansion. Rotation of embryo. Amnion. Chorion. Placenta. Embryonic and fetal g rowth. Marks of the fetal maturity. Delivery.

4. NERVOUS SYSTEM DEVELOPMENT: Neural plate, groove and tube. Brain vesicles. Development of sense organs. The eye and inner ear.

5. CIRCULATORY SYSTEM DEVELOPMENT I.: First embryonic and extraembryonic circulation. Development of major vessels. Aortal arches. Veins.

6. CIRCULATORY SYSTEM. DEVELOPMENT II.: Heart loop. Septation of the atria and ventricles. Common cardial malformations.

7. DIGESTIVE SYSTEM DEVELOPMENT I.: Delimitation of the yolk sac. Archenteron. Stomodeum. Branchial region. Teeth. Derivatives of the branchial clefts, pouches and arches. Development of Tongue.

8. DIGESTIVE and RESPIRATORY SYSTEM DEVELOPMENT: Rotation of Intestine. Liver, Pancreas and Spleen Development. Respiratory passages and Lung Development.

9. URINARY SYSTEM DEVELOPMENT: Pronephros. Mesonephros. Metanephros. Urinary passages. Cloaca.

10. GENITAL SYSTEM DEVELOPMENT: Gonade. Wolffian and Müllerian ducts. External genital organs.

11. OROFACIAL REGION, SKULL and SKELETAL DEVELOPMENT: Nose. Olfactory organ.Upper and lower jaws development. Development of the secondary Palate. Cleft malformations. Axial skeleton. Extremities. Skull. Muscles and Skin Development.

12. Problem based lecture

13. Problem based lecture

Summary of the practical sessions. Systematic histology.
General medicine 2nd year. Winter term - Kurz: Special Histology for General Medicine (cuni.cz)

1. Introduction: Revision. The rules of health security during the teaching process of Histology.
Digestive system I.: Oral cavity: tongue (radix linguae, dorsum linguae), soft palate, lip, tooth development.
2. Digestive system II.: oesophagus, stomach, duodenum, small intestine, colon, appendix vermiformis.
3. Digestive system III.: liver, gall bladder, salivary glands, pancreas.
4. Respiratory system: epiglottis, trachea, lung.
5. Urinary system: kidney, ureter, urinary bladder.
6. Male reproductive system: testis, epididymis, prostate, spermatic cord, scrotum.
7. Female reproductive system I.: ovary, uterine tube, uterus.
8. Female reproductive system II.: pregnant uterus, placenta, umbilical cord, vagina, labia minora & majora.
9. Cardiovascular and lymphatic system: myocard, aorta, femoral artery, artery and vein of the lower extremity, vessels of various organs, capillaries. lymph node, tonsils, spleen, thymus.
10. Endocrine system: hypophysis, suprarenal gland, thyroid gland, pancreas.
11. Skin: Thick and thin type - planta pedis, axilla, eyelid, auricle, mammary gland (inactive and lactating).
12. Nervous system: spinal cord, cerebellum, cerebral cortex, peripheral nerve, myelin sheath, sensitive nerve endings,
Sensory organs demonstration: eye.
13. Demonstration of embryological samples.
14. Revision of the whole topic. Examination. COURSE CREDIT

TEST 1: 20.10 - 11.11. 2023
TEST 2: 27.11. - 15.12. 2023
TEST 3: 11.12. 2023 - 5. 1. 2024
FINAL TEST: from 1. 1. 2024

Last update: Jiráková Lucie, Bc. (29.09.2023)
Course completion requirements -

The conditions for completing the course are described in the document Histology credit exam and Histology and Embryology II final exam rules in the academic year 2023/24 (see above).

Last update: Jiráková Lucie, Bc. (15.09.2023)
 
Schedule scheduled
Schedule ticket Date From - To Education type Theme Teacher Files NoteHodnocení
23aEAP0102040p1

Groups of students
2.AVSEOB
2.AVSEOB20
Wed 04.10.2023 14:00 - 15:40 lecture Fertilization and early embryonic development: Spermio- and oogenesis. Fertilization and preimplantation embryonic development. Mitochondria inheritance. Embryonic genome activation. Differentiation to embryoblast and trophectoderm. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 04.10.2023 14:00 - 15:40 lecture Fertilization and early embryonic development: Spermio- and oogenesis. Fertilization and preimplantation embryonic development. Mitochondria inheritance. Embryonic genome activation. Differentiation to embryoblast and trophectoderm. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 11.10.2023 14:00 - 15:40 lecture Blastocyst, embryo nidation, gastrulation: Blastocyst formation, blastocoel, blastocyst hatching, embryo implantation, gastrulation. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 11.10.2023 14:00 - 15:40 lecture Blastocyst, embryo nidation, gastrulation: Blastocyst formation, blastocoel, blastocyst hatching, embryo implantation, gastrulation. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 18.10.2023 14:00 - 15:40 lecture Notogenesis, embryonic disc, mesoderm and somites: Development of dorsal chord. Origin of germ layers and formation of embryonic disc. Mesoderm and somites. Mesenchyme. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 18.10.2023 14:00 - 15:40 lecture Notogenesis, embryonic disc, mesoderm and somites: Development of dorsal chord. Origin of germ layers and formation of embryonic disc. Mesoderm and somites. Mesenchyme. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 25.10.2023 14:00 - 15:40 lecture Placentation, fetal membranes, delivery: Chorionic sac, amniotic sac, and its expansion. Flexure of the embryo. Amniotic fluid. Placentation. Embryonic and fetal growth. Marks of the fetal maturity. Delivery. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 25.10.2023 14:00 - 15:40 lecture Placentation, fetal membranes, delivery: Chorionic sac, amniotic sac, and its expansion. Flexure of the embryo. Amniotic fluid. Placentation. Embryonic and fetal growth. Marks of the fetal maturity. Delivery. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 01.11.2023 14:00 - 15:40 lecture Nervous system development: Neural plate, neural groove and neural tube. Brain vesicles. Development of sense organs. The eye and inner ear. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 01.11.2023 14:00 - 15:40 lecture Nervous system development: Neural plate, neural groove and neural tube. Brain vesicles. Development of sense organs. The eye and inner ear. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 08.11.2023 14:00 - 15:40 lecture Circulatory system, part I: Embryonic yolk circulation. First embryonic circulatory system. Major vessels and aortal arches. Features of main vessels. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 08.11.2023 14:00 - 15:40 lecture Circulatory system, part I: Embryonic yolk circulation. First embryonic circulatory system. Major vessels and aortal arches. Features of main vessels. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 15.11.2023 14:00 - 15:40 lecture Circulatory system, part II: Heart tube and loop, Septation of the atria and ventricles. Common cardiac malformations. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
Wed 15.11.2023 14:00 - 15:40 lecture Circulatory system, part II: Heart tube and loop, Septation of the atria and ventricles. Common cardiac malformations. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Digestive system, part I: Delimitation of the yolk sac and primitive gut. Foregut, pharynx. Derivatives of the branchial clefts, pouches and arches. Stomodeum. Development of tongue. Development of teeth. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Digestive system, part I: Delimitation of the yolk sac and primitive gut. Foregut, pharynx. Derivatives of the branchial clefts, pouches and arches. Stomodeum. Development of tongue. Development of teeth. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Digestive system, part II & Respiratory system: Duodenum, liver, and pancreas. Midgut and rotation of intestine. Hindgut. Body cavities. Spleen development. Respiratory passages and lung development. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Digestive system, part II & Respiratory system: Duodenum, liver, and pancreas. Midgut and rotation of intestine. Hindgut. Body cavities. Spleen development. Respiratory passages and lung development. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Development of urinary system: Development of pronephros, mesonephros, and metanephros. Urinary passages. Cloaca. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Development of urinary system: Development of pronephros, mesonephros, and metanephros. Urinary passages. Cloaca. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Development of genital system: Development of gonads. Wolffian and Müllerian ducts. External genital organs. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Development of genital system: Development of gonads. Wolffian and Müllerian ducts. External genital organs. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Orofacial region, skull, and skeleton: Nose and olfactory organ. Upper and lower jaw development. Development of the secondary palate. Cleft malformations. Development of axial skeleton, extremities. Muscles and skin development. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Orofacial region, skull, and skeleton: Nose and olfactory organ. Upper and lower jaw development. Development of the secondary palate. Cleft malformations. Development of axial skeleton, extremities. Muscles and skin development. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Solving model questions for the embryology exam. Case-based discussion: Want to know if you are well prepared? Come and try solving mock exam questions before taking the official exam! Interactive problem-based lecture. Students will use their own knowledge of embryology to solve real medical problems. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Solving model questions for the embryology exam. Case-based discussion: Want to know if you are well prepared? Come and try solving mock exam questions before taking the official exam! Interactive problem-based lecture. Students will use their own knowledge of embryology to solve real medical problems. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Solving model questions for the embryology exam. Case-based discussion: Want to know if you are well prepared? Come and try solving mock exam questions before taking the official exam! Interactive problem-based lecture. Students will use their own knowledge of embryology to solve real medical problems. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
lecture Solving model questions for the embryology exam. Case-based discussion: Want to know if you are well prepared? Come and try solving mock exam questions before taking the official exam! Interactive problem-based lecture. Students will use their own knowledge of embryology to solve real medical problems. doc. Ing. Jan Nevoral, Ph.D.
průměr: 5, hodnoceno: 1x
 
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