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Pharmacology is lively scientific discipline integrating knowledge of medical education starting with anatomy, histology. To understand pharmacological principles of drug efficacy, very food knowledge of biochemistry, physiology is requested and basic knowledge of pathophysiology and pathology as well.
Having completed an undergraduate degree in Pharmacology and the ability to successively work as clinicians, undergraduate dentists receive education in prescribing drugs safely and economically and are educated in principles of drug action. Overall knowledge of general medicine pharmacology is needed to make good decision for patient in dentistry office. The main attention is focused to mechanism of action of drug, its therapeutic effect , adverse effects, also to risk of toxicity, drug-drug interactions (prescribed often by other clinician), drug-food interactions. To understand how drug acts, the content of Pharmacology teaching is based on chapters of general pharmacology and special parts. General pharmacology covers pharmacodynamics (i.e. general principles of drug action, chemical mediators, receptors and other drug targets, dose-response relationship) and pharmacokinetics, i.e. absorption, distribution, metabolism , elimination (ADME) of drug. Special parts of pharmacology are devoted to body systems (cardiovascular etc.), strategy of treatment of diseases and groups of drugs according their mechanism of action. Indications, adverse effects, drug-drug interactions , contraindications are discussed. Also the role of medicinal plants is included. Outcomes and skills: After 2 semesters of Pharmacology lessons and seminars, graduates will have knowledge in pharmacotherapy related specifically to dentistry and general knowledge in pharmacotherapy from other medicinal disciplines. The graduates will be able to integrate key elements of pharmacology to make pharmacotherapy effective, safe and economic. They will be able to provide safe and legal prescription. For actual information, they know and use drug databases. They follow regulatory authorities (EMA, FDA, SÚKL). They are able to recognize and report unexpected adverse effects. They should be opened for lifelong learning. They implement new approaches in clinical practice together with personal evaluation cost/benefit of pharmacotherapeutics. Last update: Kmoníčková Eva, doc. RNDr., CSc. (16.11.2017)
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Compulsory: Dowd Frank j. et al.: PPHARMACOLOGY AND THERAPEUTICS FOR DENTISTRY, 8th Ed., Mosby, 2025 DENTAL DRUG REFERENCE (with clinical implications) 2nd Ed., F.A. Pickett, G.T. Térézhalmy (Lippincot Williams and Wilkins), Publisher: LWW, 2009
Recommended: Neal M.J.: MEDICAL PHARMACOLOGY AT A GLANCE, 8th Ed., John Wiley & Sons, 2016 Whalen K at al.: LIPPINCOTT ILLUSTRATED REVIEWS: PHARMACOLOGY, 6th Ed., Wolters Kluwer Rang H. P.: RANG & DALE´s PHARMACOLOGY, 8th Ed., Elsevier health Sciences, 2016 Last update: Jirásko Michal, MUDr., Ph.D. (01.10.2025)
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Winter Semester Pharmacology - EA0906100
Credit requirements: Attendance at seminars, oral presentation covering latest news in pharmacy and therapeutics, submission of computer simulated experiments report and passing a credit test (covering the materials from the seminars) are compulsory. There is one regular date and two resit dates for the credit test. Credit in SIS and signed credit in Credit Book is needed.
Summer Semester Pharmacology - EA0906100
Credit requirements: Attendance at seminars, oral presentation covering latest news in pharmacy and therapeutics, submission of computer simulated experiments report and passing a credit test (covering the materials from the seminars) are compulsory. There is one regular date and two resit dates for the credit test. Credit registred in SIS is needed for the exam.
Exam requirements: Credit registred in SIS is needed for the exam..
Successful completion of a computer test and oral examination. The computer test consists of 30 randomly generated questions that have 4 possible answers, of which only 1 is correct. To successfully pass the test, you need to get 21 or more points (min. 70 % success rate). For the oral examination, the student draws 2 questions, one from general and one from special pharmacology. The list of exam questions is published in advance and is available for download in the SIS. Last update: Dědečková Eva, PharmDr. Bc. (24.02.2023)
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Seminars – winter semester: Introduction, drug development, names of drugs, clinical trials, prescription writing, and electronic prescribing in Europe. Lectures – winter semester: 1. Pharmacodynamics Last update: Bludovská Monika, MUDr., Ph.D. (01.10.2025)
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