SubjectsSubjects(version: 996)
Course, academic year 2026/2027
   
Infectious Diseases - DA1110002
Title: Infectious Diseases
Form of teaching: lecture+practicals
Guaranteed by: Department of Infectious Diseases (13-421)
Faculty: Second Faculty of Medicine
Actual: from 2025
Duration in semesters: 1
Semester: winter
Points: 4
E-Credits: 4
Examination process: winter s.:
Hours per week, examination: winter s.:0/90, C+Ex [HT]
Extent per academic year: 3 [weeks]
Capacity: unknown / unlimited (unknown)
Maximum number of enrolled students: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Repeated enrollment: 1 / 1 / 1 / 1
Guarantor: MUDr. Dita Smíšková, Ph.D.
Teacher(s): doc. MUDr. Dušan Pícha, CSc.
Classification: Medicine > Clinical Disciplines
Pre-requisite : DA1108038, DA1108363, DA1108369
Files Comments Added by
download Rozvrh_K2_ZS 2026 oprava mot.pdf Livie Krajčová
download Rozvrh_ZS_K1_mot_2026.pdf Livie Krajčová
Annotation
Infections diseases caused by viruses, bacteria, parasites, fungi. Differential diagnosis of infectious diseases, neuroinfection of both adults and children, respiratory and exanthematous illnesses, alimentary infections in children and adults, essentials of laboratory diagnosis of infectious diseases and immunisation.
Last update: Greňo Václav (20.03.2025)
Course completion requirements

Requirements for a credit:

• participation in practice (3 absences are tolerated only )

• presence at three consulting lessons ( neuroinfectious, respiratory and exanthematic infections and gastrointestinal infections) – the questions are available on the MOODLE website

• elaboration of the patient case report

More than three absences – must be compensated completely, the form will be determined by the management of the clinic

Last update: Greňo Václav (20.03.2025)
Literature
Hobstová, J.: Infectious diseases : Karolinum, 2003 (A), 2012 (D)
+Long, S.: Principles and practice of pediatric infectious diseases : Churchill Livingstone, 2010

+Mandel, G. L.: Mandell, Douglas, and Bennet's principles and practice of infectious diseases :

Elsevier Saunders, 2015

+Betts, A. F.: Reese and Bet‘s practical approach to infectious diseases : Lippincott, 2003

+Cohen J.: Infectious diseases: Mosby, 2010

+Steffen, R.: Mannual of travel medicine and health. 3nd ed., 2007

+Manual of Childhood Infection: The Blue Book (Oxford Specialist Handbooks in Paediatrics) 4th Edition 2016 (available as ebook)

+ Estee Torok and col.: Oxford Handbook of Infectious Diseases and Microbiology, 2nd Edition, 2016

+ Murray, Rosenthal,Pfaller.: Medical Microbiology, 8th Edition, 2015)

Last update: Greňo Václav (20.03.2025)
Teaching methods - Czech

The subject includes the following teaching methods:

  • seminars
  • practical exercises
  • practice

The internship takes place at clinical inpatient facilities according to the student's choice or the recommendation of the subject guarantor, always based on a valid contractual relationship between the healthcare facility and the 2nd Faculty of Medicine, Charles University.

Last update: Greňo Václav (10.07.2025)
Course assessment methods and requirements for successful completion, grading scheme

Infectious Diseases - International students, 5th year

Examination : practical part and theoretical part

Exam dates: the following week after a 3-week practice, 1-3 days (morning and afternoon)

Examining Board: 1-2 members

2nd resit: 3-member commission, the course of the exam is entered in the report and submitted to the study department - Circular No. 1/2001

The last term of exam: the exact date is written by the Dean

Exam questions:

1 Invasive meningococcal disease

Paresis of infectious origin, including polyradiculoneuritis

Culture methods for identification of infectious agents

2 Acute tonsillopharyngitis – including differential diagnosis

Foodborne intoxication, botulism

Antibiotic treatment of urinary tract infections

3 Infections in splenectomized patients and pregnant women

Bacillary dysentery and dysentery-like syndrome – differential diagnosis of hemorrhagic colitis

Interpretation of complete blood count parameters and inflammatory markers

4 Meningeal syndrome – differential diagnosis

Viral hepatitis with fecal–oral transmission

Intestinal protozoal infections (amoebiasis, giardiasis, cryptosporidiosis)

5 Jaundice and elevation of liver enzymes of infectious origin – differential diagnosis

Antibiotic treatment of streptococcal infections

Pertussis, diphtheria

6 Sepsis and septic shock (pathophysiology, clinical presentation)

Infectious mononucleosis syndrome

Vaccination – types of vaccines, basic vaccination rules, adverse effects, contraindications

7 Infections caused by S. pneumoniae and H. influenzae

Healthcare-associated infections (definition, most common infections, prevention options)

Intestinal parasitic infections (enterobiasis, ascariasis)

8 Purulent meningitis – diagnosis and treatment

Antifungal agents (overview of basic groups and indications)

Malaria

9 Tick-borne encephalitis

Infectious causes of regional lymphadenopathy + differential diagnosis

Indications for immunoglobulin use in infectious diseases

10 Purulent meningitis in neonates and infants

Hemorrhagic/petechial exanthema

Antibiotic treatment of anaerobic infections

11 Infective endocarditis

Acute diarrhea syndrome (etiology, clinical presentation, differential diagnosis)

Antiviral agents (overview of basic groups and indications)

12 Treatment of neuroinfections

Salmonella infections including typhoid and paratyphoid fever

Tropical arboviral infections (Dengue, Zika, Chikungunya, Yellow fever)

13 Pneumonia – clinical presentation, therapy, and possible complications

Antibiotic treatment of staphylococcal infections

Gastrointestinal infections caused by Escherichia coli

14 Cough of infectious origin and its differential diagnosis

Infections caused by S. pyogenes

Antibiotic treatment of neonates and pregnant and breastfeeding women

15 Diagnostic approach to the febrile patient

Risks and management of animal bites

Tularemia, bartonellosis

16 Infectious causes of generalized lymphadenopathy + differential diagnosis

Listeriosis

Antibiotic treatment of intracellular bacterial pathogens

17 Fungal infections (candidiasis, aspergillosis, mucormycosis)

Antibiotic treatment of resistant Gram-negative bacteria

Fifth disease and sixth disease

18 Treatment of respiratory infections (symptomatic therapy, indications for antibiotic use)

HIV – etiology, epidemiology, clinical presentation

Viral gastrointestinal infections

19 Treatment of sepsis

Infections caused by HSV

Traveler’s diarrhea

20 Maculopapular exanthema – most common infectious agents, differential diagnosis

Antibiotic treatment of resistant Gram-positive bacteria

Leptospirosis

21 HIV infection – diagnosis, therapy, prophylaxis

Infections of the spine, bones, and joints

Lyme borreliosis

22 Treatment and prophylaxis of tetanus

Toxin-mediated syndromes other than CDI (TSS, PVL…)

Measles, rubella, mumps

23 Skin and soft tissue infections (impetigo, erysipelas, skin abscess, necrotizing fasciitis)

Treatment of gastrointestinal infections (symptomatic therapy, indications for antibiotic use)

Infections caused by enteroviruses

24 Aseptic CNS infections (main etiological agents, clinical manifestations)

Indications for corticosteroid use in infectious diseases

Fever after return from the tropics

25 Infections in immunosuppressed patients (basic principles, febrile neutropenia, infections in patients on biologic therapy and after organ transplantation)

Methods of indirect detection of infectious agents

Infections caused by Clostridioides difficile

26 Cerebrospinal fluid findings (aseptic and purulent), indications and performance of lumbar puncture

Non-culture methods of direct detection of infectious agents

Infections caused by EBV and CMV

27 Vesiculopustular exanthema

Antibiotics – basic principles of therapy and its risks, AwaRe classification, antibiotic stewardship

Viral hepatitis with parenteral transmission

28 Viral respiratory infections (influenza, COVID-19, RSV)

Immunopathological complications of infections (erythema nodosum, PIMS, Kawasaki disease, Guillain–Barré syndrome)

Vaccination schedule in the Czech Republic and recommended childhood vaccinations

29 Pneumonia – etiological agents, diagnosis, differential diagnosis

Microorganisms potentially usable as biological weapons (anthrax, variola, viral hemorrhagic fevers)

Toxoplasmosis

30 Infections in high-risk populations (intravenous drug users, homeless individuals, alcohol-dependent patients…)

Infections caused by chlamydiae and mycoplasmas

Tissue helminth infections – toxocariasis, echinococcosis

31 Antibiotic treatment of skin and soft tissue infections

Opportunistic infections in HIV/AIDS patients

Infections caused by VZV

32 Fever – most common causes, differential diagnosis

Vaccination – recommendations for high-risk patient groups (elderly, splenectomized patients, pregnant women)

Campylobacteriosis, yersiniosis

33 Purulent meningitis – etiology, clinical presentation

Vertically transmitted infections

Pre-travel counseling (basic principles of vaccination, antimalarial prophylaxis, travel medical kit)

Last update: Krajčová Livie (13.03.2026)
Syllabus

Syllabus - Infectious Diseases for International Students

The study is organised in blocks according to the timetable.

Place: Department of Infectious Diseases, Hospital Na Bulovce, Budínova 2, Prague 8

Beginning: 8,00

Duration: three weeks

Prerequisite: Internal medicine, Pharmacology, Microbiology, Epidemiology

Conditions of obtaining credit: participation, consultations

Cloakroom: on the 5th floor

Lectures and seminars:

Neuroinfections - purulent and aseptic meningitis, polyradiculoneuritis (doc. Pícha)

Laboratory diagnostics (doc. Pícha)

Antibiotics and chemoterapeutic agents (doc.Pícha)

Exanthematic diseases (prim. Roháčová)

Higly dangerous infections (prim. Roháčová)

Gastrointestinal infections (dr. Ambrožová)

Respiratory infections (dr. Trojánek)

Vaccination ( dr. Trojánek)

Viral hepatitis (dr.Stejskal)

Parasitic diseases (dr. Stejskal)

Slides of infectious diseases (dr. Stejskal)

Infective endocarditis (dr. Smíšková)

Zoonozes (dr. Smíšková)

Infectious of immunocompromised patiens ( dr. Smíšková)

AIDS (prof. Machala)

Practical demonstration and training:

demonstration of interesting cases (assistants, doc. Pícha, prim. Roháčová

demonstration of patients with AIDS in out-patient department on the 2nd floor (prof. Machala)

lumbar puncture (assistants)

daily checking allocated patient and working on case report for the exam

Last update: Greňo Václav (20.03.2025)
 
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