Biology II. - DA1103040

• Title: Biology II.
• Guaranteed by: Department of Biology and Medical Genetics (13-716)
• Faculty: Second Faculty of Medicine
• Actual: from 2024
• Semester: winter
• Points: 6
• E-Credits: 6
• Examination process: winter s.:
• Hours per week, examination: winter s.:28/42, C+Ex [HS]
• Extent per academic year: 14 [weeks]
• Capacity: unlimited / unlimited (unknown)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Guarantor: RNDr. Eduard Kočárek, Ph.D.
• Teacher(s): RNDr. Šárka Bendová, Ph.D.; Mgr. Miroslava Hančárová, Ph.D.; RNDr. Eduard Kočárek, Ph.D.; doc. RNDr. Jaroslav Mareš, CSc.; Mgr. Darina Prchalová, Ph.D.; prof. Ing. Zdeněk Sedláček, DrSc.; MUDr. Pavel Tesner, Ph.D.; doc. MUDr. Markéta Vlčková, Ph.D.
• Classification: Medicine > Basic Sciences
• Co-requisite : DA1104339
• Pre-requisite : DA1101001, DA1102338
• Is co-requisite for: DA1104339
• Is pre-requisite for: DA1105038, DA1105439, DA1105340

Annotation

Cell biology, basis of genetics, cytogenics, molecular basis of inheritance, basis of immunology and immunogenetics, cell signaling, ontogenesis, carcinogenesis, phylogenesis

Last update: Kovář Jan (01.07.2022)

Literature

Literature for Biology I. + II.

• Your notes from lectures and practical classes and presentations and other materials from classes archived in MS Teams.

• Pritchard DJ and Korf BR. Medical Genetics at a Glance. Wiley-Blackwell, 2013.

• Passarge E. Color Atlas of Genetics. Thieme Verlag, 2017.

• Tobias ES, Connor M and Ferguson-Smith M. Essential Medical Genetics, Wiley, 2011.

Last update: Dimitriou Alena, Bc. (12.09.2023)

Syllabus

MEDICAL BIOLOGY II.

second year, winter term

Ecology and ecogenetics 1

principles of ecology, interspecific relationships, parasitism

Ecology and ecogenetics 2

environmental and genetic polymorphism ecogenetics and pharmacogenetics molecular taxonomy and molecular epidemiology

Human molecular genetics 1

structure and organisation of the human genome

Human molecular genetics 2

variability and expression of the human genome

Human molecular genetics 3

molecular basis of human hereditary diseases

Human molecular genetics 4

methods used to study the human genome and in diagnostics problems of modern human genetics

Immunogenetics

innate, adaptive mechanisms, cellular and humoral immune response, phases of immun. response, blood groups and HLA antigenes, immunoglobulins, structure, combinatory diversification, alelic exclusion, alternative splicing

Cell signalling

types of signalling, receptors, ligands, signalling mediated by G protein, secondary messengers

Carcinogenesis 1

malignant cells, antitumor mechanisms, tumor types, monoclonal theory, mutagenesis, cancerogenesis, multistep and multifactorial theory, invasivity, metastatic proces

Carcinogenesis 2

cell proliferation, regulation, proto and oncogenes, tumor supresor genes, oncogenic viruses hereditary malignancies

Evolution 1

molecular and prebiotic evolution, evolutionary theories genetic background of evolutionary processes

Evolution 2

evolution of life on Earth, human evolution

New approaches in biomedicine

gene therapy, stem cells and cell therapy

Last update: Kovář Jan (01.07.2022)