SubjectsSubjects(version: 953)
Course, academic year 2023/2024
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Immunology - DA0105044
Title: Immunology
Guaranteed by: Department of Immunology (13-722)
Faculty: Second Faculty of Medicine
Actual: from 2021
Semester: winter
Points: 6
E-Credits: 6
Examination process: winter s.:
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Extent per academic year: 14 [weeks]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: prof. MUDr. Jiřina Bartůňková, DrSc.
Classification: Medicine > Basic Sciences
Pre-requisite : DA0103337
Is pre-requisite for: DA0108369
Annotation
Courses in Basic Immunology and Immunopatology
Last update: HABET (02.11.2012)
Course completion requirements

Oral examination: 2 out of 50 questions

Last update: Nováková Irena (08.09.2017)
Literature

Abbas, A. K.: Cellular and molecular immunology : Elsevier, 2012 (B) (2015 - available as ebook)

Murphy, K. M.: Janeway’s immunobiology. Garland science, 2012 (B)

Paul, W. E: Fundamental immunology. Lippincott Williams & Wilkins, 2013.7th ed.

Rich, R. R.: Clinical immunology : principles and practice. Elsevier Saunders, 2013. 4th ed.

Last update: Nováková Irena (08.09.2017)
Requirements to the exam

Exam Questions

1.Central and peripheral lymphoid organs

2.The origine and differentiation of immunocompetent cells

3.Nonspecific immunity

4.Specific immunity

5.Humoral immunity

6.Cellular immunity

7.Nonimmunological defense mechanisms

8.Monocyte-macrophages

9.Granulocytes, types and function

10.Phagocytosis

11.Killing mechanisms of phagocytic cells, cytotoxic T lymphocytes and NK cells

12.Complement and its function

13.NK cells, surface molecules, function

14.Cytokines and their role in immune reaction

15.Antigen processing and presentation

16.HLA class I, structure, function

17.HLA class II, structure, function

18.Lymphocytes T, differentiation, subpopulations

19.Membrane molecules of T-lymphocytes and their function

20.Lymphocytes TH1

21.Lymphocytes TH2

22.Lymphocytes B, developement and differentiation

23.Imunoglobulins G and M, structure and function

24.Imunoglobulin A, structure and function

25.Imunoglobulin E, structure and function

26.Primary and secondary antibody response

27.Mucosal immunity

28.Immune mechanisms in defense against parasites

29.Immune mechanisms in defense against bacterial infections

30.Immune mechanisms in defense against viral infections

31.Immune mechanisms in defense against tumors

32.Immunopatological reaction type I-anaphylactic

33.Immunopatological reaction type II-cytotoxic

34.Immunopatological reaction mediated by immune complexes

35.Immunopatological reaction mediated by T-lymphocytes

36.Pathogenesis of the septic shock

37.Mechanism of action of antireceptor antibodies

38.Immunological reactions involved in transplant rejection

39.Graft versus host reaction

40.The causes of autoimmune diseases

41.Mechanisms of central and peripheral tolerance

42.Organ based autoimmune diseases

43.Systemic autoimmune diseases

44.Antibody deficiencies

45.Combine immunodeficiencies

46.Immune deficiency induced by HIV infection

47.Aquired disorders of immunity

48.Possibilities of suppression of immune response

49.Possibilities of stimulation of immune response

50.Vaccination

Last update: Nováková Irena (08.09.2017)
Syllabus

Immune system, overview. Phagocytic cells, complement. Communication between cells of immune systems, adhesion molecules, cytokines.

Antigen processing and presentation, HLA I and II class.

Specific (adaptive) immunity T and B lymphocytes

Immunity against infection

Immunodeficiency,vaccination

Immunity against tumors.

Immunology of transplantation.

Autoimmunity.Immunopathology.

Immunopathological reactions, allergy.

Immunotherapy

Clinical aspects of immune disorders

Last update: Nováková Irena (08.09.2017)
 
Schedule scheduled
Schedule ticket Date From - To Education type Theme Teacher Files Note
23aDA0105044p1

Groups of students
M3.2.AVSEOB
Wed 04.10.2023 10:00 - 11:40 lecture Introduction to immunology, immune organs, innate immune cells, PAMP/DAMP, phagocytosis MUDr. Adam Klocperk, Ph.D.
Wed 11.10.2023 10:00 - 11:40 lecture Inflammation, antigen presentation, MHC system, APC doc. RNDr. Daniel Smrž, Ph.D.
Wed 18.10.2023 10:00 - 11:40 lecture Complement and other humoral components of the innate immune system, NK cells, ILC MUDr. Adam Klocperk, Ph.D.
Wed 25.10.2023 10:00 - 11:40 lecture Adaptive immunity, T lymphocytes,gdT, NKT prof. PharmDr. Jitka Palich Fučíková, Ph.D.
Wed 01.11.2023 10:00 - 11:40 lecture Germinal center reaction, B lymphocytes, humoral immune response MUDr. Michaela Nováková
Wed 08.11.2023 10:00 - 11:40 lecture Immunity against infection, mucosal and skin immunity Mgr. Irena Adkins, Ph.D.
Wed 15.11.2023 10:00 - 11:40 lecture Immunopathology, autoimmunity doc. MUDr. Tomáš Milota, Ph.D.
Wed 22.11.2023 10:00 - 11:40 lecture Immunodeficiency MUDr. Adam Klocperk, Ph.D.
Wed 29.11.2023 10:00 - 11:40 lecture Allergic diseases, atopy MUDr. Marta Sobotková
Wed 06.12.2023 10:00 - 11:40 lecture Transplantation immunity doc. MUDr. Zuzana Ozaniak Střížová, Ph.D.
Wed 13.12.2023 10:00 - 11:40 lecture Biological therapy, immunostimulation/suppression MUDr. Jana Kayserová, Ph.D.
Wed 20.12.2023 10:00 - 11:40 lecture Active/passive immunization prof. MUDr. Jiřina Bartůňková, DrSc. taught by Dr. Havlišová
Wed 03.01.2024 10:00 - 11:40 lecture Antitumor immunity RNDr. Lenka Palová Jelínková, Ph.D.
Wed 10.01.2024 10:00 - 11:40 nothing prof. MUDr. Jiřina Bartůňková, DrSc.
23aDA0105044x01

Groups of students
M3.2.AVSEOB
Fri 06.10.2023 10:45 - 12:25 practicals Introduction + essay topics MUDr. Adam Klocperk, Ph.D.
Fri 13.10.2023 10:45 - 12:25 independent study project work on essay prof. MUDr. Jiřina Bartůňková, DrSc.
Fri 20.10.2023 10:45 - 12:25 independent study project work on essay prof. MUDr. Jiřina Bartůňková, DrSc.
Fri 27.10.2023 10:45 - 12:25 independent study project work on essay prof. MUDr. Jiřina Bartůňková, DrSc.
Fri 03.11.2023 10:45 - 12:25 practicals Routine immunology lab examinations prof. MUDr. Jiřina Bartůňková, DrSc. taught by Ing. Rataj
Fri 10.11.2023 10:45 - 12:25 internship Visit to the outpatients office doc. MUDr. Zuzana Ozaniak Střížová, Ph.D. Dr. Střížová, Dr. Kubešová
Fri 17.11.2023 10:45 - 12:25 nothing prof. MUDr. Jiřina Bartůňková, DrSc.
Fri 24.11.2023 10:45 - 12:25 practicals Allergoimmuno case reports doc. MUDr. Zuzana Ozaniak Střížová, Ph.D.
Fri 01.12.2023 10:45 - 12:25 practicals PID workshop, case reports MUDr. Markéta Bloomfield, Ph.D.
Fri 08.12.2023 10:45 - 12:25 practicals Translational research in immunology RNDr. Zuzana Paračková, Ph.D.
Fri 15.12.2023 10:45 - 12:25 practicals Oral presentations doc. MUDr. Tomáš Milota, Ph.D.
Fri 22.12.2023 10:45 - 12:25 nothing prof. MUDr. Jiřina Bartůňková, DrSc.
Fri 05.01.2024 10:45 - 12:25 practicals Oral presentations MUDr. Adam Klocperk, Ph.D.
Fri 12.01.2024 10:45 - 12:25 nothing prof. MUDr. Jiřina Bartůňková, DrSc.
 
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