Medical Biology II - DA0103040

• Title: Medical Biology II
• Guaranteed by: Department of Biology and Medical Genetics (13-716)
• Faculty: Second Faculty of Medicine
• Actual: from 2022
• Semester: winter
• Points: 10
• E-Credits: 10
• Examination process: winter s.:
• Hours per week, examination: winter s.:2/3, C+Ex [HT]
• Extent per academic year: 14 [weeks]
• Capacity: unknown / unlimited (unknown)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Guarantor: prof. Ing. Zdeněk Sedláček, DrSc.
• Classification: Medicine > Basic Sciences
• Pre-requisite : DA0101438, DA0102338
• Is pre-requisite for: DA0105037, DA0105439, DA0105340, DA0105341
• Is interchangeable with: DA0103039

Annotation

Last update: Mgr. Jana Čechová (25.09.2018)

Cell biology, basis of genetics, cytogenics, molecular basis of inheritance, basis of immunology and immunogenetics, cell signaling, ontogenesis, carcinogenesis, phylogenesis

Literature

Last update: Mgr. Jana Čechová (25.09.2018)

Presentations from lectures, practicals and seminars
(available on MOODLE)

Pritchard, D.: Medical genetics at a glance. Blackwell publishing, 2003 (B)
+Passarge, E.: Color atlas of genetics.Thieme Verlag, 2001, 2007 (B)

+Mange, E. J.: Basic human genetics. Sinauer associates Inc, 1999

Syllabus

Last update: Mgr. Jana Čechová (25.09.2018)

MEDICAL BIOLOGY II.

second year, winter term

Ecology and ecogenetics 1

principles of ecology, interspecific relationships, parasitism

Ecology and ecogenetics 2

environmental and genetic polymorphism ecogenetics and pharmacogenetics molecular taxonomy and molecular epidemiology

Human molecular genetics 1

structure and organisation of the human genome

Human molecular genetics 2

variability and expression of the human genome

Human molecular genetics 3

molecular basis of human hereditary diseases

Human molecular genetics 4

methods used to study the human genome and in diagnostics problems of modern human genetics

Immunogenetics

innate, adaptive mechanisms, cellular and humoral immune response, phases of immun. response, blood groups and HLA antigenes, immunoglobulins, structure, combinatory diversification, alelic exclusion, alternative splicing

Cell signalling

types of signalling, receptors, ligands, signalling mediated by G protein, secondary messengers

Carcinogenesis 1

malignant cells, antitumor mechanisms, tumor types, monoclonal theory, mutagenesis, cancerogenesis, multistep and multifactorial theory, invasivity, metastatic proces

Carcinogenesis 2

cell proliferation, regulation, proto and oncogenes, tumor supresor genes, oncogenic viruses hereditary malignancies

Evolution 1

molecular and prebiotic evolution, evolutionary theories genetic background of evolutionary processes

Evolution 2

evolution of life on Earth, human evolution

New approaches in biomedicine

gene therapy, stem cells and cell therapy