|
|
|
||
|
The subject Infection and tropical medicine is addressed to students of general medicine, 5th year.
Students learn pathogenesis, clinical presentation, diagnostics, differential diagnosis and principles of therapy of infectious diseases. The spectrum of diseases follows the actual needs of the subject in Europe with more focus on the Czech Republic.
Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
|
|
||
|
The primary goal is to teach students to diferentiate infectious diseases, to diagnose them and adopt the principles of treatment. Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
|
|
||
|
PPT presentations from the seminars available in Výuka Hobstova J (ed.): Infectious Diseases. 2nd ed. Charles University in Prague, Karolinum Press 2012 Banister BA, Begg NT, Gillespie SH. Infectious Disease. 2nd ed. Blackwell Science Ltd. Oxford 2000 Wilks D, Farrington M, Rubinstein D. The Infectious Diseases Manual. 2nd ed. Blackwell Science Ltd. Oxford 2003 whichever textbook of Infectious diseases
For microbiology knowledge augmentation, any of the following: Murray P, Rosenthal KS, Pfaller MA. Medical Microbiology, 8th ed., Elsevier Mosby 2015 Goering R, Dockrell H, Zuckerman M, Chiodini P. Mims' Medical Microbiology and Immunology. https://www.elsevier.com/books/mims-medical-microbiology-and-immunology/goering/978-0-7020-7154-6 Barer MR, Irving WL. Medical Microbiology. A Guide to Microbial Infections: Pathogenesis, Immunity, Laboratory Investigation and Control . 19th Ed. https://www.us.elsevierhealth.com/medical-microbiology-9780702072000.html Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
|
|
||
|
Teaching methods: seminars, simulated practices with presentation of case reports, bedside training. The teaching is onsite. We recommend students to prepare for each topic by individual study from the literature recommended in SIS and presentations available in Výuka. Please, follow carefully the time-table in Výuka and/or in the e-Calendar. The start of lessons each day was assessed at 8,15 AM. Students are expected to come to the 6th floor of the Department of Infectious Diseases, building no. 7 in the University Hospital Bulovka. The entrance for staff and students is from the bridge on the 2nd floor. Students should bring their stethoscopes, FFP2 respirators and hospital shoes, at the department they will receive gowns. The only but strict requirement for being granted with the credit is 80% attendance at classes. The complete course consists of 20 two-hour units: 10 seminars, 7 virtual clinical training lessons and 3 bedside training lessons. Absence in 2 days is permitted, regardless of seminar or clinical training. We recommend a full attendance, as at the exam we require information provided at classes. Compensation for missed classes will be allowed by attendance of the missed classes with other study group in the further course of the academic year. It is not possible to compensate the missed classes in the form of extra classes or practices at the infectious diseases department. Last update: Džupová Olga, doc. MUDr., Ph.D. (03.09.2024)
|
|
||
|
The credit will be given to the student upon completion of the mandatory attendance and will be written into SIS immediately after the course. It will not be possible to register for the exam without credit. The oral exam will take place onsite at the department in the winter or summer exam period. During both semesters, a limited amount of preterm exam dates will be assessed.
Exam questions for the subject Infectious and geographic medicine, 5th year, revision 2024
Part A (general infectology + organ-oriented approach/problém areas)
1. Physiological microbial flora, its role in the pathogenesis of infectious diseases
2. Sepsis: definition, pathophysiology, diagnostics
3. Acute tonsillopharyngitis
4. Acute stenosing laryngitis and epiglottitis
5. Community-acquired pneumonia
6. Nosocomial pneumonia
7. Purulent infections of the central nervous system
8. Nonpurulent (aseptic) infections of the central nervous system
9. Diarrhoea of infectious origin, incl. imported infections
10. Infections of the skin and connective tissues (joints, bones)
11. Diff. diagnosis of exanthema infections
12. Overview of CNS infections + diff. diagnostics
13. Infectious diseases with paresis
14. Overview of liver infections + diff. diagnostics
15. Diff. diagnosis of lymphadenopathy, mesenteric lymphadenopathy
16. Fever of unknown origin (except imported)
17. Fever in patient returning from tropics
18. Infective endocarditis
19. Urinary tract infections
20. Congenital and perinatal infections
21. Biological weapons (general principles of use; anthrax, variola, botulism)
22. Toxic shock syndrome
23. Healthcare associated infections (signifikance, classification, predisposition, prevention)
24. Catheter-related infections
25. Infections in immunocompromised patients
26. Infections in intravenous drug users and homeless people
27. Microbiological diagnostic methods for direct detection of pathogens
28. Microbiological diagnostic methods for indirect detection of pathogens
Part B (therapy and prevention of infectious diseases)
1. Corticosteroids in infectious diseases
2. Principles of rational antibiotic therapy (antibiotic stewardship)
3. Penicillins
Drugs, antibacterial spectrum, indications, doses, administration, adverse effects
4. Cephalosporins, carbapenems
Drugs, antibacterial spectrum, indications, administration, adverse effects
5. Vancomycin, clindamycin, linezolid
Drugs, antibacterial spectrum, indications, administration, adverse effects
6. Aminoglycosides, colistin
Drugs, antibacterial spectrum, indications, administration, adverse effects
7. Quinolones, rifampicin, chloramphenicol
Drugs, antibacterial spectrum, indications, administration, adverse effects
8. Macrolides, tetracyclines
Drugs, antibacterial spectrum, indications, administration, adverse effects
9. Cotrimoxazol, nitrofurantoin, metronidazol
Drugs, antibacterial spectrum, indications, administration, adverse effects
10. Application of antibiotics in special situations
Pregnancy, newborns, elderly, patients with severe comorbidities
11. ATB treatment of anaerobic infections
12. ATB treatment of respirátory tract infections
13. ATB treatment of urinary tract infections
14. ATB treatment of skin, bone and joint infections
15. Principles of treatment of CNS infections
16. ATB treatment of hospital-acquired infections caused by resistant bacteria
17. Treatment of fungal infections
18. Treatment of viral infections
19. Indications for therapeutic and prophylactic administration of specific antisera
20. Complex therapy of sepsis
21. Clinical presentation and treatment of dehydration in acute diarhea
22. Principles of treatment of an animal bite injury
23. Basic recommendations for travellers to the tropics and subtropics
24. Mandatory vaccinations
25. Optional vaccinations
Part C (specific infectious diseases)
1. Infections caused by herpes simplex virus (HSV-1, HSV-2)
Clinical manifestation, diagnostics, diff. diagnostics, therapy
2. Varicella-zoster virus infections
Clinical manifestation, diagnostics, diff. diagnostics, therapy, prevention
3. Infections caused by EBV and CMV
Clinical manifestation, diagnostics, diff. diagnostics, therapy
4. Infections caused by enteroviruses
Clinical manifestation, diagnostics, diff. diagnostics, therapy
5. Influenza, covid-19 and other viral respiratory tract infections
Etiology, clinical manifestation, complications, diagnosis, therapy, prevention
6. Mumps, measles, rubella
Etiology, clinical manifestation, complications, diagnosis, therapy, prevention
7. Central European tick-borne meningoencephalitis
Etiology, clinical manifestation, diagnosis, therapy, complications, prevention
8. Viral hepatitis A, E
Etiology, clinical manifestation, diagnosis, therapy, complications, prevention
9. Viral hepatitis B, C, D
Etiology, clinical manifestation, diagnosis, therapy, complications, prevention
10. Streptococcal infections
Clinical manifestation, diagnosis, diff. diagnosis, therapy, complications
11. Pneumococcal infections
Clinical manifestation, diagnosis, therapy, complications
12. Staphylococcal infections
Clinical manifestation, diagnosis, therapy, complications
13. Meningococcal infections
Clinical manifestation, diagnosis, therapy, complications, prevention
14. Infections caused by Escherichia coli: intestinal + extraintestinal disease
15. Salmonellosis, campylobacteriosis, shigellosis
Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications
16. Colitis due to Clostridioides difficile
Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications
17. Tularemia, bartonellosis, listeriosis
Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy
18. Diseases caused by neurotoxins (tetanus, botulism)
Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications, prevention
19. Spirochetal infections (Lyme disease, leptospirosis)
Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications
20. Mycoplasma and Chlamydia infections
Etiology, clinical manifestation, diagnostics, diff. diagnostics, therapy
21. Fungal infections (Candida, Aspergillus, Cryptococcus)
Clinical manifestation, diagnosis, therapy, complications
22. Malaria
Etiology, pathogenesis, clinical manifestation, diagnosis, therapy, complications, prevention
23. Toxoplasmosis
Etiology, pathogenesis, clinical manifestation, diagnosis, therapy, complications, prevention
24. Intestinal parasitic infections (protozoal, helminthiasis)
Etiology, clinical manifestation, diagnosis, therapy, complications
25. HIV infection
Etiology, pathogenesis, classification, clinical manifestation, diagnosis, therapy, prevention
26. HIV-associated opportunistic infections.
Etiology, clinical manifestation, diagnosis, therapy
27. Tuberculosis, atypical mycobacterioses
Etiology, clinical manifestation, diagnosis, therapy, prevention
Last update: Džupová Olga, doc. MUDr., Ph.D. (03.09.2024)
|
|
||
|
Seminars: Patophysiology, diagnostics and treatment of sepsis CNS infections HIV infection Congenital and perinatal infections Strategy and tactics of antibiotic therapy Influenza, covid-19 and other acute respiratory tract infections Hospital-acquired infections Imported infections Infections in specific host Parasitic infections Simulated practice: Exanthema infections Acute diarrhea, principles of rehydration and isolation Life-threatening infections Infections of the liver and biliary tract Clinical cases – CNS infections, infections of the spine Clinical cases – zoonotic infections, borreliosis Clinical cases – Pneumonia and another respiratory tract infections Last update: Džupová Olga, doc. MUDr., Ph.D. (04.09.2024)
|