SubjectsSubjects(version: 964)
Course, academic year 2024/2025
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Infection and Geographic Medicine - CVSE5P0045
Title: Infekční a tropické lékařství
Guaranteed by: Department of Infectious Diseases 3FM CU and UHB (12-INF)
Faculty: Third Faculty of Medicine
Actual: from 2023
Semester: both
Points: 2
E-Credits: 2
Examination process:
Hours per week, examination: 0/50, C+Ex [HS]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech, English
Teaching methods: full-time
Level:  
Note: you can enroll for the course in winter and in summer semester
Guarantor: MUDr. Hynek Bartoš, Ph.D.
doc. MUDr. Olga Džupová, Ph.D.
Classification: Medicine > Clinical Disciplines
Examination dates   Schedule   
Annotation -
The subject Infection and tropical medicine is addressed to students of general medicine, 5th year. Students learn pathogenesis, clinical presentation, diagnostics, differential diagnosis and principles of therapy of infectious diseases. The spectrum of diseases follows the actual needs of the subject in Europe with more focus on the Czech Republic.
Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
Aim of the course -

The primary goal is to teach students to diferentiate infectious diseases, to diagnose them and adopt the principles of treatment.
The secondary goal is to understand relations between microorganisms and human beings, to be aware of the global aspect of infectious diseases, to understand the specific position of antibiotic (antiinfection) therapy among other therapeutic modalities.

Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
Literature -

PPT presentations from the seminars available in Výuka

Hobstova J (ed.): Infectious Diseases. 2nd ed. Charles University in Prague, Karolinum Press 2012

Banister BA, Begg NT, Gillespie SH. Infectious Disease. 2nd ed. Blackwell Science Ltd. Oxford 2000

Wilks D, Farrington M, Rubinstein D. The Infectious Diseases Manual. 2nd ed. Blackwell Science Ltd. Oxford 2003

whichever textbook of Infectious diseases

 

For microbiology knowledge augmentation, any of the following:

Murray P, Rosenthal KS, Pfaller MA. Medical Microbiology, 8th ed., Elsevier Mosby 2015

Goering R, Dockrell H, Zuckerman M, Chiodini P. Mims' Medical Microbiology and Immunology.

https://www.elsevier.com/books/mims-medical-microbiology-and-immunology/goering/978-0-7020-7154-6

Barer MR, Irving WL. Medical Microbiology. A Guide to Microbial Infections: Pathogenesis, Immunity, Laboratory Investigation and Control . 19th Ed.

https://www.us.elsevierhealth.com/medical-microbiology-9780702072000.html

Last update: Džupová Olga, doc. MUDr., Ph.D. (15.02.2024)
Teaching methods -

Teaching methods: seminars, simulated practices with presentation of case reports, bedside training.

The teaching is onsite. We recommend students to prepare for each topic by individual study from the literature recommended in SIS and presentations available in Výuka. Please, follow carefully the time-table in Výuka and/or in the e-Calendar.

The start of lessons each day was assessed at 8,15 AM. Students are expected to come to the 6th floor of the Department of Infectious Diseases, building no. 7 in the University Hospital Bulovka. The entrance for staff and students is from the bridge on the 2nd floor. Students should bring their stethoscopes, FFP2 respirators and hospital shoes, at the department they will receive gowns.

The only but strict requirement for being granted with the credit is 80% attendance at classes. The complete course consists of 20 two-hour units: 10 seminars, 7 virtual clinical training lessons and 3 bedside training lessons. Absence in 2 days is permitted, regardless of seminar or clinical training. We recommend a full attendance, as at the exam we require information provided at classes. 

Compensation for missed classes will be allowed by attendance of the missed classes with other study group in the further course of the academic year. It is not possible to compensate the missed classes in the form of extra classes or practices at the infectious diseases department.

Last update: Džupová Olga, doc. MUDr., Ph.D. (03.09.2024)
Requirements to the exam -

The credit will be given to the student upon completion of the mandatory attendance and will be written into SIS immediately after the course. It will not be possible to register for the exam without credit.

The oral exam will take place onsite at the department in the winter or summer exam period. During both semesters, a limited amount of preterm exam dates will be assessed.

  

Exam questions for the subject Infectious and geographic medicine, 5th year, revision 2024

 

Part A (general infectology + organ-oriented approach/problém areas)

 

1.      Physiological microbial flora, its role in the pathogenesis of infectious diseases

 

2.      Sepsis: definition, pathophysiology, diagnostics

 

3.      Acute tonsillopharyngitis

 

4.      Acute stenosing laryngitis and epiglottitis

 

5.      Community-acquired pneumonia

 

6.      Nosocomial pneumonia

 

7.      Purulent infections of the central nervous system

 

8.      Nonpurulent (aseptic) infections of the central nervous system

 

9.      Diarrhoea of infectious origin, incl. imported infections

 

10.  Infections of the skin and connective tissues (joints, bones)

 

11.  Diff. diagnosis of exanthema infections

 

12.  Overview of CNS infections + diff. diagnostics

 

13.  Infectious diseases with paresis

 

14.  Overview of liver infections + diff. diagnostics

 

15.  Diff. diagnosis of lymphadenopathy, mesenteric lymphadenopathy

 

16.  Fever of unknown origin (except imported)

 

17.  Fever in patient returning from tropics

 

18.  Infective endocarditis

 

19.  Urinary tract infections

 

20.  Congenital and perinatal infections

 

21.  Biological weapons (general principles of use; anthrax, variola, botulism)

 

22.  Toxic shock syndrome

 

23.  Healthcare associated infections (signifikance, classification, predisposition, prevention)

 

24.  Catheter-related infections

 

25.  Infections in immunocompromised patients

 

26.  Infections in intravenous drug users and homeless people

 

27.  Microbiological diagnostic methods for direct detection of pathogens

 

28.  Microbiological diagnostic methods for indirect detection of pathogens

           

 

Part B (therapy and prevention of infectious diseases)

 

1.      Corticosteroids in infectious diseases

 

2.      Principles of rational antibiotic therapy (antibiotic stewardship)

 

3.      Penicillins

Drugs, antibacterial spectrum, indications, doses, administration, adverse effects

 

4.      Cephalosporins, carbapenems

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

5.      Vancomycin, clindamycin, linezolid

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

6.      Aminoglycosides, colistin

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

7.      Quinolones, rifampicin, chloramphenicol

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

8.      Macrolides, tetracyclines

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

9.      Cotrimoxazol, nitrofurantoin, metronidazol

Drugs, antibacterial spectrum, indications, administration, adverse effects

 

10.  Application of antibiotics in special situations

Pregnancy, newborns, elderly, patients with severe comorbidities

 

11.  ATB treatment of anaerobic infections

 

12.  ATB treatment of respirátory tract infections

 

13.  ATB treatment of urinary tract infections

 

14.  ATB treatment of skin, bone and joint infections

 

15.  Principles of treatment of CNS infections

 

16.  ATB treatment of hospital-acquired infections caused by resistant bacteria

 

17.  Treatment of fungal infections

 

18.  Treatment of viral infections

 

19.  Indications for therapeutic and prophylactic administration of specific antisera

 

20.  Complex therapy of sepsis

 

21.  Clinical presentation and treatment of dehydration in acute diarhea

 

22.  Principles of treatment of an animal bite injury

 

23.  Basic recommendations for travellers to the tropics and subtropics

 

24.  Mandatory vaccinations

 

25.  Optional vaccinations

 

 

Part C (specific infectious diseases)

 

1.      Infections caused by herpes simplex virus (HSV-1, HSV-2)

Clinical manifestation, diagnostics, diff. diagnostics, therapy

 

2.      Varicella-zoster virus infections

Clinical manifestation, diagnostics, diff. diagnostics, therapy, prevention

 

3.      Infections caused by EBV and CMV

Clinical manifestation, diagnostics, diff. diagnostics, therapy

 

4.      Infections caused by enteroviruses

Clinical manifestation, diagnostics, diff. diagnostics, therapy

 

5.      Influenza, covid-19 and other viral respiratory tract infections

Etiology, clinical manifestation, complications, diagnosis, therapy, prevention

 

6.      Mumps, measles, rubella

Etiology, clinical manifestation, complications, diagnosis, therapy, prevention

 

7.      Central European tick-borne meningoencephalitis

Etiology, clinical manifestation, diagnosis, therapy, complications, prevention

 

8.      Viral hepatitis A, E

Etiology, clinical manifestation, diagnosis, therapy, complications, prevention

 

9.      Viral hepatitis B, C, D

Etiology, clinical manifestation, diagnosis, therapy, complications, prevention

 

10.  Streptococcal infections

Clinical manifestation, diagnosis, diff. diagnosis, therapy, complications

 

11.  Pneumococcal infections

Clinical manifestation, diagnosis, therapy, complications

 

12.  Staphylococcal infections

Clinical manifestation, diagnosis, therapy, complications

 

13.  Meningococcal infections

Clinical manifestation, diagnosis, therapy, complications, prevention

 

14.  Infections caused by Escherichia coli: intestinal + extraintestinal disease

 

15.  Salmonellosis, campylobacteriosis, shigellosis

Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications

 

16.  Colitis due to Clostridioides difficile

Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications

 

17.  Tularemia, bartonellosis, listeriosis

Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy

 

18.  Diseases caused by neurotoxins (tetanus, botulism)

Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications, prevention

 

19.  Spirochetal infections (Lyme disease, leptospirosis)

Etiology, clinical manifestation, diagnosis, diff. diagnosis, therapy, complications

 

20.  Mycoplasma and Chlamydia infections

Etiology, clinical manifestation, diagnostics, diff. diagnostics, therapy

 

21.  Fungal infections (Candida, Aspergillus, Cryptococcus)

Clinical manifestation, diagnosis, therapy, complications

 

22.  Malaria

Etiology, pathogenesis, clinical manifestation, diagnosis, therapy, complications, prevention

 

23.  Toxoplasmosis

Etiology, pathogenesis, clinical manifestation, diagnosis, therapy, complications, prevention

 

24.  Intestinal parasitic infections (protozoal, helminthiasis)

Etiology, clinical manifestation, diagnosis, therapy, complications

 

25.  HIV infection

Etiology, pathogenesis, classification, clinical manifestation, diagnosis, therapy, prevention

 

26.  HIV-associated opportunistic infections.

Etiology, clinical manifestation, diagnosis, therapy

 

27.  Tuberculosis, atypical mycobacterioses

Etiology, clinical manifestation, diagnosis, therapy, prevention

 

 

Last update: Džupová Olga, doc. MUDr., Ph.D. (03.09.2024)
Syllabus -

Seminars:

Patophysiology, diagnostics and treatment of sepsis

CNS infections

HIV infection

Congenital and perinatal infections 

Strategy and tactics of antibiotic therapy

Influenza, covid-19 and other acute respiratory tract infections

Hospital-acquired infections 

Imported infections

Infections in specific host 

Parasitic infections

Simulated practice:

Exanthema infections

Acute diarrhea, principles of rehydration and isolation

Life-threatening infections 

Infections of the liver and biliary tract

Clinical cases – CNS infections, infections of the spine 

Clinical cases – zoonotic infections, borreliosis 

Clinical cases – Pneumonia and another respiratory tract infections

Last update: Džupová Olga, doc. MUDr., Ph.D. (04.09.2024)
 
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