Genetics of susceptibility to infectious diseases - CPVL105
Title: Genetics of susceptibility to infectious diseases
Guaranteed by: Department of Medical Genetics 3FM CU (12-GEN)
Faculty: Third Faculty of Medicine
Actual: from 2023
Semester: winter
Points: 1
E-Credits: 1
Examination process: winter s.:
Hours per week, examination: winter s.:0/15, C [HS]
Capacity: unknown / unknown (20)
Min. number of students: 5
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: doc. Marie Lipoldová, CSc.
Comes under: AVSEOB-PVK-3 (ZÁPIS)
AVSEOB-PVK-4 (ZÁPIS)
AVSEOB1-PVK-3 (ZÁPIS)
AVSEOB1-PVK-4 (ZÁPIS)
Pre-requisite : C1VL001
Examination dates   Schedule   
Annotation
For the students of the 2nd, 3rd and 4th. This course is offered each academic year.
Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Aim of the course

To provide students with an integrated view of the principal mechanisms of genetic susceptibility to infectious diseases, with an emphasis on new developments.

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Course completion requirements

70% attendance, short answers to basic questions.

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Literature

Goering R, Dockrell H, Zuckerman M, Chiodini PL. Mims' Medical Microbiology and Immunology, 7th Edition, Elsevier, 2024 (or 6th Edition, Elsevier 2019)

Delves PJ, Martin SJ, Burton DR, Roitt IM: ROITT’s Essential Immunology, 13th edition, Wiley Blackwell, 2017

Turnpenny PD, Ellard S, Cleaver R. Emery's Elements of Medical Genetics and Genomics, 16th Edition, Elsevier 2022

Journals: Nature, Science, Nature Genetics, Nature Reviews Genetics, Nature Reviews Immunology, Nature Biotechnology…

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Requirements to the exam

70% attendance, short answers to basic questions.

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Syllabus

• Overview of basic terms in description of infectious diseases

• Overview of basic terms and methods in genetics of susceptibility to diseases

• Genes influencing susceptibility to SARS-CoV-2

• Genes influencing susceptibility to HIV

• Natural selection during the Black Death

• Genetic influence on susceptibility to bacterial sepsis

• Genetic influence on susceptibility to Mycobacterium leprae

• Genetic influence on susceptibility to tuberculosis

• Genes controlling susceptibility to malaria

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)
Entry requirements

Basic knowledge in genetics and immunology of infectious diseases.

Last update: Lipoldová Marie, doc., CSc. (08.01.2024)