State Examination in Paediatrics - CPADXX36R
Title: Dětské lékařství
Guaranteed by: Department of Children and Adolescents 3FM CU and UHKV (12-KDD)
Faculty: Third Faculty of Medicine
Actual: from 2025
Semester: both
Points: 0
E-Credits: 0
Examination process:
Hours per week, examination: 0/0, STEX [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech, English
Teaching methods: full-time
Level:  
Note: deregister from the exam date if a requisite was not fulfilled
you can enroll for the course in winter and in summer semester
Guarantor: doc. MUDr. Felix Votava, Ph.D.
doc. MUDr. Jan David, Ph.D.
Classification: Medicine > Clinical Disciplines
Examination dates   Schedule   
Annotation -
The examination builds upon the previous instruction in propedeutics and pediatrics. It focuses on the etiology, pathophysiology, symptomatology, diagnosis, differential diagnosis, and treatment of age-specific diseases. The examination includes a practical part—examination, diagnosis, and treatment proposal for a specific patient. The theoretical part of the exam also includes a question from clinical genetics.
Last update: David Jan, doc. MUDr., Ph.D. (21.05.2025)
Aim of the course -
The objective is to complete pediatric education for 6th-year students to the extent required for the state final exam and the graduate profile.
Last update: David Jan, doc. MUDr., Ph.D. (21.05.2025)
Literature -

Marcdante KJ, Kliegman RM. Nelson Essentials of Pediatrics. Elsevier, 2018.

Bláhová K, Fencl F, Lebl J, et al. Pediatrická propedeutika. Galén, 2019.  

David J, Votava F, et al. Diferenciální diagnostika vybraných pediatrických stavů. Grada, 2025. 

Janota J, Straňák Z, et al. Neonatologie. EEZY, 2023. 

Lebl J, Janda J, Pohunek P, Starý J, et al. Klinická pediatrie. Galén, 2014.  

Mixa V, Heinige P, Vobruba V, et al. Dětská přednemocniční a urgentní péče. Grada, 2024. 

Muntau AC. Pediatrie. Grada, 2014.  

Last update: David Jan, doc. MUDr., Ph.D. (21.05.2025)
Teaching methods -

Part of state examination in pediatrics.

Last update: David Jan, doc. MUDr., Ph.D. (21.05.2025)
Requirements to the exam -

State examination in pediatrics. Questions for the state exam in pediatrics (from 2025/2026):

General Issues, Neonatology 

Specific Diseases 

Differential Diagnosis 

Physiological growth and its assessment 

Cystic fibrosis 

Hematuria 

Psychomotor retardation 

Diabetic ketoacidosis 

Proteinuria 

Puberty and its disorders 

Autoinflammatory diseases 

Oedema 

Breastfeeding and other infant nutrition 

Exanthematous diseases 

Dysuria 

Foreign body issues in digestive and respiratory tract 

Thyroid diseases 

Arterial hypertension 

Enteral and parenteral nutrition 

Glomerulonephritis

Dyspnoea 

Child abuse syndrome 

Adrenal gland diseases 

Cough 

Acid-base balance disorders 

Anaemias 

Recurrent respiratory infections 

Injuries and intoxications 

Obesity 

Gait disorders, limping 

Neonatal screening 

Acute kidney injury 

Joint pain 

Cardiopulmonary resuscitation 

Vasculitis 

Microcephaly, macrocephaly 

Vaccination 

Nephrotic syndrome 

Hepatosplenomegaly 

Pharmacotherapy in paediatrics 

Neuroinfections 

Polyuria, polydipsia 

Malnutrition and failure to thrive 

Allergic diseases, anaphylaxis 

Hypoglycaemia, hyperglycaemia 

Neonatal jaundice 

Acute laryngitis and epiglottitis 

Hyponatraemia, hypernatraemia 

Respiratory disorders in the newborn 

Acquired heart diseases 

Abdominal pain 

Sepsis 

Calcium-phosphate metabolism disorders 

Anorexia 

Characteristics of the physiological newborn 

Diabetes mellitus 

Gastrointestinal bleeding 

Prematurity, postmaturity, complications 

Inherited disorders of carbohydrate and lipid metabolism 

Diarrhoea 

Shock 

Leukaemias and lymphomas 

Constipation 

Neonatal infections 

Lower respiratory tract diseases 

Vomiting 

Dehydration 

Non-specific intestinal inflammation and coeliac disease 

Headache 

Congenital anomalies of the urinary system 

Tuberculosis 

Seizures 

Congenital anomalies of the respiratory system 

Haemostasis disorders 

Meningeal syndrome 

Congenital heart defects 

Liver and biliary tract diseases 

Consciousness disorders 

Immunity and immune disorders 

Solid tumours 

Sore throat 

Psychomotor development 

Eating disorders 

Lymphadenopathy 

Characteristics of childhood, classification, specifics 

Inherited disorders of amino acid metabolism 

Chest pain 

Congenital anomalies of the gastrointestinal tract 

Urinary tract infections 

Hypokalemia, hyperkalemia 

Growth disorders 

Cardiac arrhythmias 

Fever 

Questions from Clinical Genetics for 6th Year – State Examination from Pediatrics (from 2025/2026):

 

1.      Reproduction genetics, preconception genetic testing

2.      Preimplantation genetic testing – indications, types and techniques

3.      Noninvasive screening in the 1st and in the 2nd trimester of pregnancy

4.      Invasive prenatal diagnostics in the 1st and in the 2nd trimester of pregnancy

5.      Postnatal (newborn) screening and predictive (presymptomatic) testing

6.      Teratogenic factors and congenital abnormalities, risk groups of pharmaceuticals

7.      Cytogenetic examinations of chromosomal abnormalities

8.      Molecular genetic examinations of monogennic diseases

9.      Multifactorial diseases – risk calculation, genetic testing, significance of epigenom

10.  Possibilities of therapy of genetic diseases, including gene therapy

11.  Syndromes associated with numerical abnormalities of chromosomes

12.  Syndromes associated with structural aberrations of chromosomes, also microdeletion

13.  Syndromes of chromosomal instability

14.  Hereditary tumour diseases, diagnostics, possibilities of prevention

15.  Molecular changes in neoplasia – at the level of chromosomes and DNA

16.  Genetic causes of mental retardation, diagnostics

17.  Genetic causes of immunity disorders, monogenic and polygenic, within syndromes

18.  Genetic examinations in cardiology, diagnostics, examples of diseases

19.  Monogenic diseases affecting the nervous system

20.  Monogenic diseases affecting the endocrine system

21.  Monogenic diseases affecting haematopoesis and haemocoagulation

22.  Monogenic diseases affecting the sense organs

23.  Monogenic diseases affecting the connective tissue

24.  Monogenic diseases affecting the skin

25.  Monogenic diseases affecting the muscles

26.  Monogenic diseases affecting the skeletal system

27.  Diseases associated with expansion of repetitive sequences

28.  Gene imprinting and associated syndromes

29.  Lysosomal storage disorders and mitochondrial diseases

30.  Familial hypercholesterolemia and Smith-Lemli-Opitz syndrome

Last update: David Jan, doc. MUDr., Ph.D. (02.10.2025)
Syllabus -
Review of physical examination of neonates, infants, toddlers, preschool and school-aged children, and adolescents; pediatric medical history. Interpretation of laboratory and imaging methods in pediatrics. Special emphasis is placed on: neonatology, pneumology, allergology and immunology, rheumatology, gastroenterology, endocrinology and diabetology, hematology and oncology, nephrology, clinical genetics, clinical nutrition and metabolic disorders, intensive care and resuscitation; and primary pediatric care. 
Last update: David Jan, doc. MUDr., Ph.D. (21.05.2025)