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Course, academic year 2024/2025
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ERASMUS - Infection and Geographic Medicine - CERA5P0077
Title: ERASMUS - Infekční a tropické lékařství
Guaranteed by: Department of Infectious Diseases 3FM CU and UHB (12-INF)
Faculty: Third Faculty of Medicine
Actual: from 2023
Semester: both
Points: 2
E-Credits: 2
Examination process:
Hours per week, examination: 0/50, C(+Ex) [HS]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Level:  
Note: you can enroll for the course in winter and in summer semester
Guarantor: MUDr. Hynek Bartoš, Ph.D.
doc. MUDr. Olga Džupová, Ph.D.
Classification: Medicine > Clinical Disciplines
Examination dates   Schedule   
Annotation -
The subject Infection and tropical medicine is addressed to students of general medicine, 5th year. Students learn pathogenesis, clinical presentation, diagnostics, differential diagnosis and principles of therapy of infectious diseases. The spectrum of diseases follows the actual needs of the subject in the Czech Republic.
Last update: Kubánek Ondřej (10.10.2013)
Aim of the course -

The primary goal is to teach students to diferentiate infectious diseases, to diagnose them and adopt the principles of treatment.

The secondary goal is to understand relations between microorganisms and human beeings, to be aware of the global aspect of infectious diseases, to understand the specific position of antibiotic (antiinfection) therapy among other therapeutic modalities.

Last update: Kubánek Ondřej (10.10.2013)
Literature -

Jirina Hobstova (ed.): Infectious Diseases. 2nd edition. Charles University in Prague, Karolinum Press 2012
Barbara A. Bannister, Norman T. Begg, Stephen H. Gillespie: Infectious Disease. 2nd edition. Blackwell Science Ltd. Oxford 2000
Norman R. Grist, Darrel O. Ho-Yen, Eric Walker, Glyn R. Williams: Diseases of Infection. An Illustrated Textbook. 2nd edition. Oxford University Press Inc. New York, 1994
David Wilks, Mark Farrington, David Rubinstein: The Infectious Diseases Manual. 2nd edition. Blackwell Science Ltd. Oxford 2003

Last update: Kubánek Ondřej (10.10.2013)
Teaching methods -

Teaching methods:

seminars, bedside training

Last update: Kubánek Ondřej (10.10.2013)
Requirements to the exam -

Questions for exam in Infection and geographic medicine, General medicine, 5th year

 

 

Part I:  Organ-oriented approach and special situations

 

1.      Acute tonsillopharyngitis (sore throat) syndrome

 

2.      Acute epiglottitis, laryngitis and laryngotracheitis

 

3.      Community-acquired pneumonia

 

4.      Purulent meningitis (incl. neonatal age)

 

5.      Aseptic meningitis and encephalitis

 

6.      Acute diarrhoea

 

7.      Skin and musculoskeletal infections of bacterial origin

 

8.      Infectious diseases with maculopapular exanthem

 

9.      Infectious diseases with vesicular and pustular exanthem

 

10.  General overview of liver infections. Parenchymatic infections diffuse and focal, hepatobiliary infections

 

11.  Upper and lower urinary tract infections

 

12.  Infective endocardititis

 

13.  Lymphadenopathy and lymfatic tissue infections

 

14.  Sepsis, septic shock

 

15.  Fever of unknown origin. Diagnostic approach, common causes in temperate climatic zones.

 

16.  Fever in patient returning from tropics

 

17.  Diarrhoea in patient returning from tropics

 

18.  Infectious diseases during pregnancy. Congenital and perinatal infections.

 

19.  Biological weapons, with emphasis on anthrax.

 

20.  Animal bite infections (lyssa, cat-scratch disease).

 

21.  Hospital-acquired infections.

 

 

Part II :          Pathogen-oriented approach

 

1.      Influenza

 

2.      Arboviral infections (tick-borne encephalitis, dengue fever, yellow fever)

 

3.      Epidemic parotitis and enteroviral infections (Coxsackie, ECHO viruses, polioviruses)

 

4.      HSV and VZV infections

 

5.      EBV and CMV infections

 

6.      HIV infection. Routes of infection, classification, clinics, diagnosis, therapy, prognosis.

 

7.      Opportunistic infections in HIV disease. Clinics, diagnosis, therapy, prophylaxis

 

8.      Viral hepatitis A-E

 

9.      Staphylococcal infections. Toxic shock syndrome

 

10.  Streptococcal infections. Toxic shock syndrome

 

11.  Pneumococcal infections

 

12.  Meningococcal invasive disease (incl. pathogenesis)

 

13.  Salmonellosis and campylobacteriosis

 

14.  Shigella and E.coli diarhoea infections

 

15.  Spirochetal infections (esp. Lyme borreliosis, leptospirosis)

 

16.  Chlamydia and Mycoplasma infections

 

17.  Clostridial toxin-mediated diseases (esp. botulism, tetanus)

 

18.  Fungal infections in immunocompetent and immunocompromised patients

 

19.  Amoebiasis, giardiasis

 

20.  Malaria

 

21.  Intestinal helminthiases (intestinal nematodes, cestodes)

 

 

 

Part III: Antiinfective therapy

 

1.       Beta-lactam antibiotics. Subgroups, antibacterial spectra, indications, adverse effects, mechanisms of resistance.

 

2.       Penicillins. Drugs, antibacterial spectra, indications, doses, adverse effects.

 

3.       Cephalosporins. Drugs, antibacterial spectra, indications, adverse effects.

 

4.       Macrolides, lincosamides. Drugs, antibacterial spectra, indications, adverse effects.

 

5.       Tetracyclines, chloramphenicol, metronidazol. Drugs, antibacterial spectra, indications, adverse effects.

 

6.       Aminoglycosides and glycopeptides. Drugs, antibacterial spectra, indications, adverse effects. Monitoring of therapy.

 

7.       Fluoroquinolones and cotrimoxazol. Drugs, antibacterial spectra, indications, adverse effects.

 

8.       Antibiotic therapy of Gram-positive infections

 

9.       Antibiotic therapy of Gram-negative infections

 

10.   Antibiotic therapy of anaerobic infections

 

11.   Antibiotic therapy of nosocomial infections (resistant bacteria)

 

12.   Chemotherapy of fungal infections. Drugs, indications

 

13.   Chemotherapy of viral infections. Indications, drugs

 

14.   Hyperimmune specific immunoglobulins as part of complex therapy of infections

 

15.   Physiological human microbial flora and its changes due to antibiotics (incl. antibiotic - associated colitis).

 

 

80% attendance at the lessons (minimum 7 days) is required for credit. Upon late arrival beyond 15 minut after the beginning the attendance will not be recorded.

 

Last update: Džupová Olga, doc. MUDr., Ph.D. (21.10.2013)
Syllabus -

 

HIV/AIDS

 

Sepsis

 

CNS infections

 

Therapy of viral infections. Influenza.

 

Acute diarhea

 

Hospital-acquired infections

 

Congenital and perinatal infections

 

Imported and parasitic infections 

 

Life-threatening infections

 

Strategy and tactics of antibiotic therapy

 

Infectious diseases on slides (Exanthema inf., inf. eliminated by vaccination)

 

Clinical cases

 

 

Last update: Džupová Olga, doc. MUDr., Ph.D. (03.01.2018)
 
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