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Compulsory elective course. The course describes the classification, pathophysiology, clinical features prognosis and principles of the treatment of the most common malignancies of B and T cells - leukemia and lymphomas. In the theoretical part (seminars) students will learn the classification and pathophysiology, the clinical features will be demonstrated on the patients of OKH FNKV. An important part of the course represents the demonstration of the immune pathologies often accompanying lymphomas and leukemia - autoimmune syndromes such as autoimmune hemolytic anemia or immunodeficiencies. The immunotherapy changed the the prognosis of many patients suffering from lymphomas and leukemia. Students will get knowledge of the principles and results of immune-based therapies in these settings. The impact of selected original articles on the decision on treatment schedule will be discussed.
Last update: Kubánek Ondřej (21.06.2011)
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To learn the basic classification of the malignancies of B and T cells, to learn their typical clinical features, to learn to estimate their prognosis and treatment modalities. Last update: Kubánek Ondřej (21.06.2011)
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Medical Immunology. Parslow TG, Stites DP, Terr AI,. - 10th ed. - London: Mc Graw-Hill, 2001. Essentials of Clinical Immunology, Chapel H, Haeney M et al. Blackwell Science, 4th ed. 1999 Wintrobe's Clinical Hematology, 12th edition Last update: Kubánek Ondřej (21.06.2011)
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Seminars with active participation of students, practical - patient examination. Last update: Kubánek Ondřej (21.06.2011)
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Presence (75%). Last update: Kubánek Ondřej (21.06.2011)
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1. Classification and pathogenesis of the malignancies of B and T cells 2. Hodgkin?s disease 3. Non-Hodgkin lymphomas 4. Multiple myeloma a monoclonal gamapathies 5. T lymphomas 6. Leukemia 7. Imunodeficiencies, primary a secondary, therapeutic options 8. Autoimmune phenomens in patients suffering the malignancies of B and T cells 9. Immunologic basis of transplantations and immunologic interventions Last update: Kubánek Ondřej (21.06.2011)
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