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Last update: RADOVA (08.09.2008)
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Last update: RADOVA (08.09.2008)
The aim of the course is to present basic information in the field of transcription DNA as the first step in the expression of genetic information, and mechanisms that regulate transcription. Another aim is to summarize molecular changes linked to the malignant transformation of the cell and the role of transcription in this process. |
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Last update: RADOVA (08.09.2008)
Alberts B. a kol., " Základy buněčné biologie", Espero Publishing, Ústí nad Labem, 1998. Alberts B. et al.:"Molecular Biology of the Cell", 4th ed., Garland Science, N.Y. 2002.
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Last update: RADOVA (08.09.2008)
Seminar and practical demostrations. |
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Last update: Pavlína Svobodová (22.09.2010)
Attendance 90%, passing the written test with 60% of correct answers. |
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Last update: RADOVA (08.09.2008)
1. Regulation of transcription in eukaryotic cells 2. Oncoproteins of DNA viruses and tumor suppressor genes. 3. Defects in cell cycle regulation and apoptosis during malignant transformation 4. Transformation and immortalization of cells in the cell culture 5. Practical demonstration of cell cultivation and gene transfer into cultured cells 6. Clinical aspects of gene mutations in oncology |