Simulation of Biomedical Systems - B90294

• Title: Simulation of Biomedical Systems
• Guaranteed by: Institute of Pathological Physiology First Faculty of Medicine Charles University (11-00180)
• Faculty: First Faculty of Medicine
• Actual: from 2024
• Semester: both
• Points: 0
• E-Credits: 0
• Hours per week, examination: 2/0, C [HT]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: combined
• Note: course is intended for doctoral students only; course can be enrolled in outside the study plan; you can enroll for the course in winter and in summer semester
• Guarantor: doc. MUDr. Jiří Kofránek, CSc.
• Attributes: doktorské studium

Annotation

The course is primarily intended for bioengineers, physicians, biologists, and other postgraduate students in Biomedical Informatics who want to learn about the basic properties of physiological regulatory systems. The emphasis is on individual work in creating mathematical models and completing assigned homework. The course is completed with a credit and a term paper. Prerequisites: The course will take place in the computer lab of the Department of Biocybernetics at the Institute of Pathological Physiology, First Faculty of Medicine, Charles University. Basic computer skills and some preliminary mathematical knowledge are expected. Seminars and Active Participation: Work on the computer, complete homework assignments, and finish with a term paper (creating a computer model of a selected physiological system according to the assigned literature). 1. Mathematical Modeling – Models and Simulations 2. Modeling Continuous Systems in the Modelica Language 3. Modeling Discrete Behavior in the Modelica Language 4. Object-Oriented Modeling in the Modelica Language 5. Static Analysis of Biological Systems 6. Analysis of Linear Physiological Systems in the Time Domain 7. Analysis of Linear Physiological Systems in the Frequency Domain 8. Stability Analysis 9. Identification of Physiological Regulatory Systems 10. Optimization in Biological Systems 11. Nonlinear Analysis in Physiological Regulatory Systems 12. Complex Dynamics in Physiological Regulatory Systems

Last update: Machová Marie, Bc., DiS. (15.08.2024)

Course completion requirements

Obhajoba semestrální práce.

Last update: Machová Marie, Bc., DiS. (15.08.2024)

Literature

Povinná:

• Khoo, Michael C. K.. Physiological control systems : analysis, simulation, and estimation. New York: Institute of Electrical and Electronics Engineers, 2000, 319 s. ISBN 0-7803-3408-6.
• Fritzson, Petre. Principles of Object-oriented modeling and Simulation with Modelica 3.3. : IEE Press, 2015, s. ISBN 9781118859124.
• Michael M Tiller: Modelica by Example. On-line https://mbe.modelica.university/, 2022
• Willem van Meurs. Modeling and simulation in biomedical engineering. Application in Cardirespiratory Physiology. : McGrawHill, 2011, s. ISBN 0-07-171446-4.
• Feher, Joseph J.. Quantitative human physiology : an introduction. Kidlington, England: Elsevier Inc., 2017, 1 s. ISBN 0-12-801154-8.
• Marco Viceconti, Luca Emili. Toward Good Simulation Practice. Best Practices for the Use of Computational Modelling and Simulation in the Regulatory Process of Biomedical Products. : Springer, 2024, s. ISBN 978-3-031-48283-0.

Last update: Machová Marie, Bc., DiS. (15.08.2024)