The course is intended for postgraduate students in the field of Biomedical Informatics with a background in
technical or mathematical education. The aim of the course is to provide a comprehensive overview of the
functioning of the human physiological system in health and certain pathological conditions. The course is
completed with a credit and a term paper.
Prerequisites: The course will take place in the computer lab of the Department of Biocybernetics at the Institute of
Pathological Physiology, First Faculty of Medicine, Charles University. Basic computer skills and certain preliminary
mathematical knowledge are expected.
Part 1: Basic Cellular Processes: Integration and Coordination
1. Introduction - Physiology as an integrative science of regulation in the human organism.
2. Molecular Interactions
3. Cells and Tissues
4. Cellular Metabolism and Energy in Biological Systems
5. Membrane Dynamics
6. Communication, Integration, and Homeostasis Intercellular Communication
Part 2: Homeostasis and Regulation
1. Introduction to the Endocrine System
2. Neurons: Cellular and Network Properties
3. Central Nervous System
4. Efferent Part: Autonomic and Somatic Regulation of Movement
5. Muscles
6. Integrative Physiology of the Senses: Basic Properties of the Sensory System
7. Efferent Physiology: Control of Movement
Part 3: Integration of Functions
1. Cardiovascular Physiology
2. Blood Flow and Blood Pressure Regulation
3. Blood
4. Respiration – Mechanics of Breathing
5. Exchange and Transport of Blood Gases
6. Kidneys: Functional Anatomy of the Kidneys
7. Integrative Physiology: Homeostasis of Body Fluids and Electrolytes
Part 4: Metabolism, Growth, and Aging
1. Digestive System
2. Endocrine Regulation of Growth and Metabolism
3. Immune System
4. Integrative Physiology: Physical Exercise
5. Physiology of Reproduction and Development
Last update: Machová Marie, Bc., DiS. (15.08.2024)
Literature - Czech
Povinná:
. . In Silverthorn, Dee Unglaub. Human physiology : an integrated approach . Harlow: Pearson, 2019, s. -. ISBN 978-1-292-25954-3..
. . In Hall, John E.. Guyton and Hall textbook of medical physiology . London, New York: W.B.Saunders Company, 2015, s. -. ISBN 978-1455770052..
. . In Silbernagl, Stefan, Despopoulos, Agamemnon. Atlas fyziologie člověka . Praha: Grada, 2004, s. -. ISBN 80-247-0630-X..
. . In Silbernagl, Stefan, Lang, Florian. Atlas patofyziologie člověka . Praha: Grada, 2001, s. -. ISBN 80-7169-968-3..
Last update: Machová Marie, Bc., DiS. (21.08.2024)
