Introduction to Cell Biology - B83650

• Title: VP - Introduction to Cell Biology
• Guaranteed by: Institute of Histology and Embryology First Faculty of Medicine Charles University (11-00120)
• Faculty: First Faculty of Medicine
• Actual: from 2025
• Semester: both
• Points: 2
• E-Credits: 2
• Hours per week, examination: 28/0, C [HS]
• Capacity: 100
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Explanation: MUDr. Jaromír Šrámek, [e-mail]
• Note: course can be enrolled in outside the study plan; enabled for web enrollment; you can enroll for the course in winter and in summer semester
• Guarantor: doc. MUDr. Tomáš Kučera, Ph.D.
• Attributes: Teoretický předmět; Zubní lékařství

Annotation

Overview of cell biology for 1st year students. The course is based on Goodman’s Medical Cell Biology; some chapters are omitted, because they are too advanced for introductory course or they are topic of mandatory course Biology and Genetics. Place and date: room HISTS1 - Albertov4 , Thursday 16.30-18.00

Last update: Špácová Marika, DiS. (24.09.2025)

Aim of the course

English

Main goal is to offer basic knowledge of cell biology in compact form

Last update: Špácová Marika, DiS. (17.06.2025)

Course completion requirements

MCQ tests during the semester, a student has to get at least 60 % of points.

Last update: Špácová Marika, DiS. (18.06.2025)

Literature

Obligatory:

• Steven R. Goodman. Goodman's Medical Cell Biology. : Academic Press, 2020, s. ISBN 978-0-12-817927-7.

Optional:

• Alberts, Bruce, Heald, Rebecca Johnson, Alexander Morgan, David Owen, Raff, Martin C., Roberts, Keith Walter, Peter. Molecular biology of the cell. New York: W. W. Norton & Company, 2022, 1404 s. ISBN 978-0-393-88485-2.

Last update: Šrámek Jaromír, MUDr. (18.06.2025)

Syllabus

Sylabus (témata výuky) *: (neuvádí se datum a čas - tento údaj se zapisuje do datumového rozpisu)

1. Structure of the cell membrane. Membrane transport.

2. Resting and action membrane potential.

3. Microtubules and intracellular transport. Intermediate filaments.

4. Actin filaments. Mechanism of muscle contraction.

5. Proteosynthesis.

6. Endocytosis. Lysosomes.

7. Mitochondria and cell energetics.

8. Cell nucleus and regulation of gene expression.

9. Cell adhesions.

10. Extracellular matrix.

11. Cell receptors and intracellular signalling.

12. Cell cycle.

13. Cell death.

14. Stem cells. Differentiation of cells.

Suggested Book:

Steven R. Goodman: Goodman’s Medical Cell Biology. 4th Ed. Academic Press 2020

Additional Books:

Bruce Alberts: Molecular Biology of the Cell. 7th Ed. Nortona a Co. 2022

Harvey Lodish: Molecular Cell Biology. 9th Ed. Macmillan 2021

Last update: Špácová Marika, DiS. (18.06.2025)

Education plan