Based on the current measures put in place by the Faculty, the organization of the winter semester teaching will be as follows: Pathology practical classes (microscope practices, seminars) will be taught IN PERSON. The lectures will begin in person as well, they will take place in the lecture hall of the Institute of pathology, on the 2nd floor.
If there any any changes to the organization of your classes you will all be informed immediately through MS Teams and also on the website of our Institute.
Last update: Kendall Bártů Michaela, MUDr., Ph.D. (01.03.2022)
Requirements to the exam - Czech
The credit will be awarded to students after fulfilling the following conditions:
1. During the course of the semester, each student must succesfully pass all of the required self-repetition tests on Moodle. For the winter semester, that is General pathology (i.e. Pathology 1) tests available here, while for the summer semester it is the Organ (Special) pathology tests (i.e. Pathology 2) available here. In order to obtain the credit it is necessary to succesfully pass test (the result itself does not matter, the point threshold is set automatically in the system). There is no time limit to how long you can take to fill out the test. The students can take these tests in any order they wish to and at any time, provided that they have taken all of the tests by the end of summer semester.
2. Meeting the attendance requirements. During the time when in presence teaching of the practical lessons is allowed, attendance of these classes continues to be mandatory. The students are allowed to have a total of 3 "excused" (i.e. justifiably substantiated by a reason they provide their teacher with) absences for the entire semester.
The traditional slide exam will not be held this semester and as such the slide exam is NOT one of the requirements for obtaining the credit.
PATHOLOGY FINAL EXAMINATION TOPICS
GENERAL PATHOLOGYEXAMINATION TOPICS FOR STUDENTS OF GENERAL MEDICINE
GENERAL PATHOLOGY 1. Cell injury – causes, sequence of events2. Cell death - sequence of events, mechanisms, types of cell death 3. Cellular adaptation to stress - definitions, examples 4. Hypertrophy and hyperplasia 5. Atrophy 6. Metaplasia 7. Intracellular accumulations – definition, overview 8. Intracellular accumulation of lipids – steatosis, lipidoses (mechanisms, examples) 9. Intracellular accumulation of proteins (examples) 10. Amyloidosis 11. Mucopolysaccharidoses. Cystic fibrosis 12. Disorders of carbohydrate metabolism (diabetes mellitus, glycogenoses) 13. Pigments - exogenous, including pneumoconioses 14. Pigments - endogenous 15. Pathologic calcification 16. Crystals and concrements (lithiasis) 17. Heart failure – cardiac findings 18. Heart failure – left-sided versus right-sided failure 19. Hyperemia, congestion and hemorrhage 20. Edema 21. Hemostasis and thrombosis 22. Ischemia 23. Embolism 24. Infarction 25. Shock 26. Overview of inflammation – definitions, general features and causes 27. Acute inflammation – overview and summary, sequence of events 28. Morphologic patterns of acute inflammation 29. Outcomes of acute inflammation 30. Chronic inflammation (causes, cells and mediators). Morphologic features of chronic inflammation 31. Granulomatous inflammation 32. Systemic effects of inflammation 33. Local signs of inflammation 34. Overview of tissue repair 35. Cell and tissue regeneration, repair by scarring 36. Healing of skin wounds (first and second intention), abnormalities in wound healing and scarring 37. Tuberculosis – overview, pathogenesis, clinical features 38. Primary tuberculosis 39. Secondary tuberculosis 40. Sarcoidosis. Leprosy 41. Syphilis 42. Immunologically mediated tissue injury – hypersensitivity reactions 43. Autoimmune diseases (mechanisms, general features, examples of localized and systemic diseases), rejection of transplants 44. Immunodeficiency syndromes45. Genetic causes of diseases 46. Chemical, physical, and nutritional causes of diseases 47. Spectrum of inflammatory responses to infection 48. Mechanisms of viral and bacterial injury 49. Neoplasia – definitions, nomenclature, classification 50. Differentiation of tumor cells, anaplasia, dysplasia 51. Characteristics of benign, borderline and malignant neoplasms 52. Local invasion. Metastasis 53. Genetic and acquired conditions predisposing to cancer (precanceroses) 54. Cancer genes. Genetic lesions in cancer 55. Carcinogenic agents 56. Typing, grading and staging of tumors 57. Tumor-like conditions (pseudotumors) 58. Epithelial tumors – overview, characteristics, examples 59. Mesenchymal (soft tissue) tumors - overview, characteristics, examples 60. Hematopoietic and lymphoid tissue tumors - overview, characteristics, examples 61. Neuroectodermal tumors - overview, characteristics, examples 62. Germ cell tumors - overview, characteristics, examples 63. Mixed tumors - overview, characteristics, examples
ORGAN PATHOLOGY
BLOOD VESSELS 64. Hypertensive vascular disease, hypertension (systemic and pulmonary) 65. Arteriosclerosis, atherosclerosis 66. Aneurysms and dissections 67. Vasculitides 68. Diseases of veins and lymphatics 69. Tumors of blood vessels and lymphatic vessels
PATHOLOGY OF THE HEMATOPOETIC AND LYMPHOID TISSUES 79. Anemias – summary, classification 80. Myeloproliferative neoplasms 81. Myelodysplastic syndromes 82. Leukemias (acute and chronic)83. Plasma cell neoplasms and related entities 84. Histiocytic neoplasms (Langerhans cell histiocytosis) and dendritic (reticular) cell tumors 85. Bone marrow suppression, aplastic anemia 86. Bleeding disorders, DIC 87. Lymphadenopathies 88. General characteristics of lymphoid neoplasms 89. Non-Hodgkin lymphomas 90. Hodgkin lymphoma 91. Spleen pathology (splenomegaly, rupture, circulatory disorders)
RESPIRATORY SYSTEM PATHOLOGY 92. Inflammatory diseases of nose, paranasal sinuses, pharynx, larynx, and the middle ear 93. Tumors of the nose, paranasal sinuses, and pharynx 94. Tumors of larynx and trachea 95. Pulmonary diseases of vascular origin 96. Pulmonary edema 97. Pulmonary embolism 98. Acute respiratory distress syndrome (diffuse alveolar damage) 99. Atelectasis, collapse, emphysema 100. Chronic obstructive lung diseases 101. Chronic bronchitis, bronchiectasis, asthma 102. Pulmonary emphysema 103. Chronic interstitial (restrictive) lung diseases 104. Pulmonary infections – classification 105. Bacterial pneumonias – morphologic patterns 106. Pulmonary tuberculosis 107. Granulomatous inflammations of the lung 108. Tumors of the bronchi and lungs
PATHOLOGY OF THE PLEURA, MEDIASTINUM, AND THYMUS 109. Pathological content of the pleural cavity 110. Pleuritis 111. Tumors of the pleura 112. Pathology of the mediastinum and thymus ORAL CAVITY AND GASTROINTESTINAL TRACT 113. Oral cavity inflammations, proliferative lesions of the oral cavity, odontogenic cysts 114. Diseases of teeth and supporting structures (dental caries and their complications, gingivitis, periodontitis) 115. Tumors and precancerous lesions of the oral cavity, odontogenic tumors 116. Diseases of salivary glands – nonneoplastic 117. Diseases of salivary glands - neoplasms 118. Non-neoplastic diseases of esophagus (malformations, esophageal diverticula, hiatal hernia, esophageal achalasia) 119. Non-neoplastic diseases of esophagus – inflammations, esophageal varices 120. Esophageal tumors121. Gastropathy and acute gastritis 122. Chronic gastritis 123. Complications of chronic gastritis - peptic ulcer disease 124. Gastric polyps and tumors 125. Intestinal obstruction 126. Vascular disorders of bowel 127. Malabsorption 128. Infectious enterocolitis 129. Inflammatory bowel disease (IBD) and other non-infectious intestinal inflammations 130. Acute appendicitis 131. Inflammatory intestinal disease – sigmoid diverticula and diverticulitis 132. Colonic polyps and polyposes 133. Tumors of the intestine (epithelial, mesenchymal, lymphomas, neuroendocrine tumors) 134. Diseases of the peritoneum, hernias, prolapse
LIVER, BILE DUCTS, AND PANCREAS 135. General features of liver disease – mechanisms of injury and repair (necrosis, apoptosis, scar formation) 136. Liver failure and cirrhosis, cholestatic syndromes 137. Viral hepatitis, autoimmune hepatitis 138. Drug- and toxin-induced liver injury 139. Alcoholic and nonalcoholic fatty liver disease 140. Inherited metabolic liver diseases (hemochromatosis, Wilson disease, α1- antitrypsin deficiency) 141. Diseases of the intrahepatic and extrahepatic biliary tree 142. Circulatory disorders of the liver 143. Nodules and tumors of the liver 144. Non-neoplastic disorders of the gallbladder and extrahepatic biliary tree 145. Tumors of the gallbladder and extrahepatic biliary tree 146. Cystic fibrosis of the pancreas 147. Inflammations of the pancreas 148. Pancreatic neoplasms
KIDNEY AND ITS COLLECTING SYSTEM, LOWER URINARY TRACT 149. Cystic diseases of the kidney, congenital and developmental anomalies 150. Glomerular diseases – summary, mechanisms of injury, classification 151. Primary glomerular diseases – diseases associated mostly with nephrotic syndrome 152. Primary glomerular diseases – diseases associated mostly with hematuria/nephritic syndrome 153. Rapidly progressive glomerulonephritis, glomerulonephritis secondary to systemic disease (lupus nephritis, diabetic nephropathy) 154. Diabetic nephropathy 155. Renal diseases affecting tubules and interstitium 156. Renal diseases involving blood vessels – nephrosclerosis and malignant hypertension157. Tumors of the kidney 158. Non-neoplastic diseases of the lower urinary tract (urinary outflow obstruction etc.) 159. Tumors of the lower urinary tract
MALE GENITAL SYSTEM 160. Nonneoplastic diseases of prostate, penis and testis 161. Tumors of the prostate and penis 162. Testicular neoplasms
FEMALE GENITAL SYSTEM AND BREAST 163. Nonneoplastic diseases of the vulva and vagina 164. Tumors of the vulva and vagina 165. Nonneoplastic diseases and premalignant lesions of the uterine cervix 166. Tumors of the uterine cervix 167. Nonneoplastic diseases of the uterine body 168. Tumors and precanceroses of the uterine body 169. Diseases of fallopian tubes, ectopic pregnancy 170. Ovarian cysts 171. Epithelial tumors of the ovary 172. Germ cell tumors, sex cord stromal tumors and mixed tumours of the ovary 173. Gestational trophoblastic disease 174. Diseases of pregnancy and placenta (placental abnormalities, inflammations and infections of the placenta, ectopic pregnancy, preeclampsia/eclampsia) 175. Clinical presentations of breast disease, nonneoplastic diseases of the breast 176. Tumors of the breast
CENTRAL NERVOUS SYSTEM AND PERIPHERAL NERVES 177. Edema, intracranial hypertension, herniation, and hydrocephalus 178. Cerebrovascular diseases 179. Congenital malformations, neurocutaneous syndromes, traumatic parenchymal injuries 180. Infections of the nervous system 181. Prion diseases, metabolic and toxic encephalopathies 182. Diseases of myelin 183. Neurodegenerative diseases 184. Tumors of brain, meninges, peripheral nerves 185. Pathology of the eye
BONES, JOINTS, AND MUSCLES 186. Osteopenia and osteoporosis 187. Fractures and their healing, osteonecrosis 188. Metabolic osteopathies (rickets and osteomalacia, hyperparathyroidism-related bone disorders, renal osteodystrophy) 189. Osteomyelitis, bone tuberculosis, Paget ́s disease 190. Bone tumors and tumorlike lesions 191. Nonneoplastic diseases of joints (arthritis, arthrosis)192. Joint tumors and tumorlike conditions 193. Disorders of skeletal muscle ENDOCRINE SYSTEM 194. Non-neoplastic and tumor diseases of the pituitary gland, pituitary syndromes 195. Adrenocortical hyperfunction and insufficiency 196. Neoplasms of the adrenal cortex and medulla 197. Nonneoplastic thyroid diseases and thyroidal syndromes 198. Thyroid neoplasms 199. Diseases of parathyroid glands
DIABETES MELLITUS 200. Diabetes mellitus
SKIN 201. Non-infectious dermatitides (acute inflammatory dermatoses, chronic inflammatory dermatoses, blistering disorders) 202. Infectious dermatoses and inflammatory disorders of dermis and hypodermis 203. Epithelial lesions and tumors of the skin 204. Mesenchymal tumors of the skin 205. Melanocytic lesions and tumors of the skin
PEDIATRIC DISEASES 206. Prematurity and fetal pathology prior to birth, damage during labour (perinatal infections, perinatal injuries, fetal hydrops...) 207. Complications of the perinatal period – respiratory distress syndrome of the newborn, bronchopulmonary dysplasia, retinopathy, necrotizing enterocolitis, newborn sepsis) 208. Tumors of children and adolescents
PATHOLOGY OF SYSTEMIC INFECTIONS 209. Infections caused by herpetic viruses, viral exanthemas 210. Respiratory viral and bacterial infections 211. Infections caused by Gram-positive bacteria 212. Infections caused by Gram-negative bacteria 213. Primarily enteropathogenic bacterial infections 214. Clostridial and chlamydial infections, zoonoses, diseases transmitted by insects 215. Mycoses 216. Parasitic diseases (toxoplasmosis, malaria, amoebiasis, giardiasis, trichomoniasis, leischmaniosis, trypanosomiasis, taeniasis, ascariasis)
Last update: Dušková Jaroslava, prof. MUDr., CSc. (03.06.2024)
Syllabus
Winter semester topics:
Fundamentals of cell pathology.
Morphology and pathogenesis changes in organs and tissues in disease states.
General characteristics of inflammatory processes.
Morphological changes in infectious diseases.
Morphological changes in autoimmune diseases.
Morphological manifestations of rejection processes in transplants.
General oncology including principles of molecular biology diagnostics and international classifications of tumors.
Morphology of preneoplastic conditions. Role of pathologists in screening.
Summer semester topics:
Systemic organ pathology: macroscopic, histopathological changes, and molecular biology of individual diseases.
Etiopathogenesis of disease states.
Complications and healing of diseases.
Typing, grading, staging, and rating (prognosis) of tumor processes.
Introduction. Role and methods in pathology. Health, illness, causes of diseases, classification of diseases.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 4, hodnoceno: 3x
Thursday
03.10.2024
Cell damage. Necrosis, apoptosis. Fate of the damaged tissue
MUDr. Jan Stříteský, CSc.
průměr: 4, hodnoceno: 3x
Monday
07.10.2024
Pathology of organelles. Secretion process and its disorders. Lysosomes, peroxisomes, Mitochondria.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 3, hodnoceno: 3x
Thursday
10.10.2024
Amyloidosis
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 4, hodnoceno: 2x
Monday
14.10.2024
Steatosis. Glycogen disorders. Calcification.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 3, hodnoceno: 2x
Thursday
17.10.2024
Autogenous pigments
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 5, hodnoceno: 1x
Monday
21.10.2024
Haematogenous pigments. Icterus
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
24.10.2024
Exogenous pigments
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
31.10.2024
Manifestations of circulatory insufficiency
prof. MUDr. Jaroslava Dušková, CSc.
Monday
04.11.2024
Local circulatory disorders
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
07.11.2024
Inflammation I. Definition of inflammation, causes of inflammation. Pathomorphology of the acute phase of inflammation. Inflammatory exudate. Functions of individual cells, the role of mediators. Phagocytosis and its disorders. Healing of acute inflammation, resolution, organization, regeneration, wound healing, reparative processes.
prof. MUDr. Jaroslava Dušková, CSc.
Monday
11.11.2024
Inflammation II. Systematics of exudative inflammation of the skin, serous membranes, mucous membranes and interstitial inflammation.
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
14.11.2024
Inflammation III. Chronic inflammation. Granulomatous inflammatory processes. Fibroplastic processes. Immune disorders and inflammation.
prof. MUDr. Jaroslava Dušková, CSc.
Monday
18.11.2024
Infectious diseases I
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
21.11.2024
Infectious diseases II
prof. MUDr. Jaroslava Dušková, CSc.
Monday
25.11.2024
General oncology I
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
28.11.2024
General oncology II
prof. MUDr. Jaroslava Dušková, CSc.
Monday
02.12.2024
Fundamentals od molecular pathology of tumor disease. Use of molecular biological methods in molecular pathology.
Thursday
05.12.2024
Mesenchymal tumours
prof. MUDr. Jaroslava Dušková, CSc.
Monday
09.12.2024
9.12.- 13.12. 2024 Integrated course ( microbiology, pathology, infectious diseases). During this week no other pathology teaching takes place.
Monday
16.12.2024
Lymphomas and leukemias
MUDr. Jan Stříteský, CSc.
Thursday
19.12.2024
Epithelial tumours
prof. MUDr. Jaroslava Dušková, CSc.
Monday
06.01.2025
Neuroectodermal tumours
prof. MUDr. Jaroslava Dušková, CSc.
Thursday
09.01.2025
Pathology of vessels
doc. MUDr. Eva Honsová, Ph.D.
Monday
13.01.2025
Cardiovascular malformations. Pathology of the endocardium
doc. MUDr. Kristýna Němejcová, Ph.D.
Thursday
16.01.2025
Pathology of the myocardium
doc. MUDr. Kristýna Němejcová, Ph.D.
Monday
20.01.2025
Pathology of the respiratory system I
prof. MUDr. Ctibor Povýšil, DrSc.
Thursday
23.01.2025
Pathology of the respiratory system II
prof. MUDr. Ctibor Povýšil, DrSc.
Rozpis datumový
Den
Datum
Popis
Učitel
Soubory
Poznámka
Hodnocení
Pondělí
30.09.2024
Introduction. Role and methods in pathology. Health, illness, causes of diseases, classification of diseases.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 4, hodnoceno: 3x
Čtvrtek
03.10.2024
Cell damage. Necrosis, apoptosis. Fate of the damaged tissue
MUDr. Jan Stříteský, CSc.
průměr: 4, hodnoceno: 3x
Pondělí
07.10.2024
Pathology of organelles. Secretion process and its disorders. Lysosomes, peroxisomes, Mitochondria.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 3, hodnoceno: 3x
Čtvrtek
10.10.2024
Amyloidosis
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 4, hodnoceno: 2x
Pondělí
14.10.2024
Steatosis. Glycogen disorders. Calcification.
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 3, hodnoceno: 2x
Čtvrtek
17.10.2024
Autogenous pigments
prof. MUDr. Jaroslava Dušková, CSc.
průměr: 5, hodnoceno: 1x
Pondělí
21.10.2024
Haematogenous pigments. Icterus
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
24.10.2024
Exogenous pigments
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
31.10.2024
Manifestations of circulatory insufficiency
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
04.11.2024
Local circulatory disorders
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
07.11.2024
Inflammation I. Definition of inflammation, causes of inflammation. Pathomorphology of the acute phase of inflammation. Inflammatory exudate. Functions of individual cells, the role of mediators. Phagocytosis and its disorders. Healing of acute inflammation, resolution, organization, regeneration, wound healing, reparative processes.
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
11.11.2024
Inflammation II. Systematics of exudative inflammation of the skin, serous membranes, mucous membranes and interstitial inflammation.
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
14.11.2024
Inflammation III. Chronic inflammation. Granulomatous inflammatory processes. Fibroplastic processes. Immune disorders and inflammation.
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
18.11.2024
Infectious diseases I
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
21.11.2024
Infectious diseases II
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
25.11.2024
General oncology I
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
28.11.2024
General oncology II
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
02.12.2024
Fundamentals od molecular pathology of tumor disease. Use of molecular biological methods in molecular pathology.
Čtvrtek
05.12.2024
Mesenchymal tumours
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
09.12.2024
9.12.- 13.12. 2024 Integrated course ( microbiology, pathology, infectious diseases). During this week no other pathology teaching takes place.
Pondělí
16.12.2024
Lymphomas and leukemias
MUDr. Jan Stříteský, CSc.
Čtvrtek
19.12.2024
Epithelial tumours
prof. MUDr. Jaroslava Dušková, CSc.
Pondělí
06.01.2025
Neuroectodermal tumours
prof. MUDr. Jaroslava Dušková, CSc.
Čtvrtek
09.01.2025
Pathology of vessels
doc. MUDr. Eva Honsová, Ph.D.
Pondělí
13.01.2025
Cardiovascular malformations. Pathology of the endocardium