Basic Immunology - B83123 (General Medicine - English parallel)

• Title: Basic Immunology
• Guaranteed by: Institute Institute of Medical Microbiology First Faculty of Medicine and General University Hospital in Prague (11-00351)
• Faculty: First Faculty of Medicine
• Actual: from 2024
• Semester: summer
• Points: 4
• E-Credits: 4
• Examination process: summer s.:
• Hours per week, examination: summer s.:1/0, MC [HT]
• Extent per academic year: 15 [hours]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Explanation: MUDr. Jitka Petanová, [e-mail], tests: Mgr. Nováková [e-mail]
• Note: enabled for web enrollment
• Guarantor: prof. RNDr. Jiří Hrdý, Ph.D.
• Comes under: Compulsory for GM 2.y._24/25
• Attributes: Lékařství; Teoretický předmět
• Pre-requisite : B83009
• Interchangeability : B82078
• Is co-requisite for: B80382
• Is pre-requisite for: B83163
• In complex pre-requisite: B80033, B80080, B82946

Annotation

English

Structure of the immune system, its regulation and cooperation between separate components in physiologic and pathologic situations. Antigen presentation.

Last update: Kolářová Jana (10.02.2020)

Czech

Struktura a základními mechanismy imunitního systému, s regulacemi a kooperací jednotlivých složek obranných mechanismů za fyziologických podmínek i patologických stavů.

Last update: Kolářová Jana (10.03.2021)

Aim of the course

Gives basic information about the function of the immune system.

Last update: Kohútová Vladislava, Ing. (07.01.2019)

Literature

English

Kuby Immunology (7th, Seventh Edition) - By Owen, Punt, & Stranford Textbook Binding - January 1, 2013

Playfair, Chain: Immunology at a Glance. Blackwell Publ., 2005

Nairn, Roderick, Helbert, Matthew: Immunology for Medical Students. ELSEVIER HEALTH SCIENCES, 2007.

Stites, D.P. Basic and clinical immunology

Paul, W.E. Fundamental immunology

Janeway, Ch.A. Immunobiology

Abbas AK: Basic Immunology: The Function of the Immune System, Saunders, 2001

Ogra PL, Mestecky J et al.(eds.) Mucosal Immunology, sec.ed., Academic Press, 1999 

 

E library (1st faculty of Medicine), http://elsevierelibrary.co.uk/bookshelf

-selected immunological chapters from 

• Medical Microbiology: Patrick R. Murray, Ken S. Rosenthal, Michael A. Pfaller, 2012

• MimMedical Microbiology: Richard Goering, Hazel Dockrell, Mark Zuckerman, Ivan M. Roitt, Peter L. Chiodini, 2012

• Medical Microbiology: David Greenwood, 2007

Last update: Kohútová Vladislava, Ing. (07.01.2019)

Czech

Šterzl, I., a kol.: Základy imunologie pro zubní a všeobecné lékaře. Nakladatelství Karolinum, Praha, 2005.

Krejsek, J., Kopecký, O.: Klinická imunologie. Nukleus HK, 2004.

Hořejší, V., Bartůňková, J.: Základy imunologie, 5. vydání. Triton, Praha, 2013.

Last update: Kohútová Vladislava, Ing. (07.01.2019)

Teaching methods

Lectures will be held in person according to the schedule

Communication with teachers via MS TEAMS (questions, possibility of consultations, information on the organization of teaching, informing about possible changes in the form of teaching)

PowerPoint presentation of lectures in SIS

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Requirements to the exam

Credit awarded on the basis of a written test (Three attempts: the first two attempts will be in the form of a test, the third in the form of an oral exam).

Exam dates will be listed in the middle of the semester. Please check the SIS for updates.

More information: Michaela Nováková, [e-mail]

 

Exam dates:

Dates will be listed in the SIS during April. Data counts (dates and locations) are finite. When enrolling, carefully read the information about the test time, look at the detail of the date!

All dates of the examination period and pre-terms will be open for student enrollment in May 2024, later dates will be open from July 2024.


Special dates:

September - oral exam = only 3rd attempt

 

Classification scale:

67% and less - insufficiently

68% - 77% - good

78% - 84% - very good

85% and more - excellent

 

Last update: Petanová Jitka, MUDr. Mgr., CSc. (12.02.2024)

Syllabus

English

Immunologic terminology.

The structure of immune system: cells, tissue, organs. Innate and specific immunity.

Phagocytosis, nature killer cells, complement system.

Antigens, HLA systems, antigen presentation.

Adhesion molecules, cytokines.

T and B lymphocytes, immunoglobulins.

Mucosal immunity.

Anti-tumor immunity.

Transplantations.

Inflammation and inflammatory response.

Immunopathologic reactions, imunopathologic states in clinical practice.

Last update: Kolářová Jana (10.02.2020)

Czech

Základní imunologická terminologie.

Struktura imunitního systému: buňky, tkáně, orgány.

Dělení imunitního systému: přirozená a specifická imunita.

Fagocytóza, přirození zabíječi, komplementový systém.

Komunikace mezi buňkami, adhezní molekuly, cytokiny.

Antigeny, HLA molekuly, prezentace antigenu, APC.

T a B lymfocyty, protilátky.

Slizniční imunita.

Protinádorová imunita, transplantace.

Zánět a zánětová odpověď.

Imunopatologické reakce, imunopatologické stavy v klinické praxi.

Last update: Kolářová Jana (10.02.2020)

Education plan

English

Schedule semestral
Educational week	Date	From - To	Education type	Theme	Teacher	Files	Note	Hodnocení
2	07.03.2025	10:45 - 12:15	lecture	Introduction to Immunology. Terminology. Structure of immune system.	prof. RNDr. Jiří Hrdý, Ph.D.		Purkynje Institute
4	21.03.2025	10:45 - 12:15	lecture	Innate immunity.	prof. RNDr. Jiří Hrdý, Ph.D.
6	04.04.2025	10:45 - 12:15	lecture	Specific immunity I. Specific immunity II	prof. RNDr. Jiří Hrdý, Ph.D.
8	18.04.2025	10:45 - 12:15	lecture	Easter holiday
10	02.05.2025	10:45 - 12:15	lecture	Inflammation. Anti-infectious immunity.	prof. RNDr. Jiří Hrdý, Ph.D.
12	16.05.2025	10:45 - 12:15	lecture	Anti-tumor immunity. Transplantations.	prof. RNDr. Jiří Hrdý, Ph.D.
14	30.05.2025	10:45 - 12:15	lecture	Immunopathologic reactions and states in clinical practice.	prof. RNDr. Jiří Hrdý, Ph.D.

Czech

Rozpis semestrální
Výukový týden	Datum	Od - Do	Typ výuky	Téma	Učitel	Soubory	Poznámka	Hodnocení
2	07.03.2025	10:45 - 12:15	přednáška	Introduction to Immunology. Terminology. Structure of immune system.	prof. RNDr. Jiří Hrdý, Ph.D.		Purkynje Institute
4	21.03.2025	10:45 - 12:15	přednáška	Innate immunity.	prof. RNDr. Jiří Hrdý, Ph.D.
6	04.04.2025	10:45 - 12:15	přednáška	Specific immunity I. Specific immunity II	prof. RNDr. Jiří Hrdý, Ph.D.
8	18.04.2025	10:45 - 12:15	přednáška	Easter holiday
10	02.05.2025	10:45 - 12:15	přednáška	Inflammation. Anti-infectious immunity.	prof. RNDr. Jiří Hrdý, Ph.D.
12	16.05.2025	10:45 - 12:15	přednáška	Anti-tumor immunity. Transplantations.	prof. RNDr. Jiří Hrdý, Ph.D.
14	30.05.2025	10:45 - 12:15	přednáška	Immunopathologic reactions and states in clinical practice.	prof. RNDr. Jiří Hrdý, Ph.D.