Genetics in Dentristry - B81142 (Dentistry)

• Title: Genetics in Dentristry
• Guaranteed by: Institute of Biology and Medical Genetics First Faculty of Medicine Charles University and General University Hospital in Prague (11-00160)
• Faculty: First Faculty of Medicine
• Actual: from 2023
• Semester: summer
• Points: 3
• E-Credits: 3
• Examination process: summer s.:
• Hours per week, examination: summer s.:1/0, C [HT]
• Extent per academic year: 15 [hours]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Additional information: http://biol.lf1.cuni.cz/menu.htm
• Note: prefer medical statement
• Guarantor: MUDr. Miroslava Švábová, CSc.
• Comes under: Compulsory for Dentistry 2.y._24/25
• Attributes: Teoretický předmět; Zubní lékařství
• Pre-requisite : B83032

Annotation

The subject aims at mastering selected genetics principles in stomatology. Genealogy, types of inheritance, monogenic traits, multifactorial inheritance. Structure and function of chromosomes, karyotype. Numerical and structural aberrations. Mutations, mutagens, molecular basis of inherited disease. Teratogenesis, inborn developmental diseaes, oncogenetics. Genetic counselling. Genealogical analysis, counselling for hereditary diseases and syndromes of the orofacial area.

Last update: Kolářová Jana (31.01.2020)

Aim of the course

The subject aims at mastering selected genetics principles in stomatology.

Last update: Kolářová Jana (31.01.2020)

Literature

English

http://ublg.lf1.cuni.cz/en/recommended-literature

Last update: KOT02392 (03.01.2014)

Syllabus

1. Syndromology a symptomatology - Introduction

2. Diagnosis

3. Amelogenesis imperfecta, dentinogenesis imperfecta and osteogenesis imperfecta- symptomatology and syndromology

4. Families with multiple teeth retention

5. Haydu - Cheney syndrome

6. Prenatal diagnostics, syndromology a symptomatology amniocentesis and ultrasound, fetal echocardiography

7. Pachydermoperiostosis

8. Congenital spine deformities and rare syndromes

9. Bone and tooth dysplasias, oligodontia, hypodontia and anodontia; celidocranial dysplasia and low bone dnesity, biomechanice and clinical aspects; mucopolysaccharidoses and oligosaccharidoses, multiple cartilagenous exostoses, enchondromatosis, osteopetrosis and pycnodysostosis; Exomphalos-Macroglossia-Gigantism Syndrome, Parkes - Weber - Klippel - Trenaunay syndrome, hemihypertrophy aand asymetry, genetic consultation

10. Goldenhar syndrome and related syndromes, abnormal vertebral segmentation, Klippel -Feil anomaly, Jarcho - Levin syndrome, facioauriculovertebral spectrum comprising spectrum hemifacial microsomia,VACTERL, VATER, NTD, anencephaly, ecephalocoele, Poland-Moebius syndrome

11. Rheumatology and genetics

12. Haematology and genetics

13. Basocellular nevus syndrome

14. Arthrogryposis multiplex congenita.

15. Duchenne myopathyand its prenatal diagnostics

16. Pierre- Robin anomaly

17. Cerebrocostomandibular syndrome.

18. Syndromology of situs viscerum inversus.

Last update: Kolářová Jana (31.01.2020)