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Course, academic year 2024/2025
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Pharmacology 2 - B80386 (General Medicine - English parallel)
Title: Pharmacology 2
Guaranteed by: Institute of Pharmacology First Faculty of Medicine Charles University and General University Hospital in Prague (11-00190)
Faculty: First Faculty of Medicine
Actual: from 2023
Semester: winter
Points: 3
E-Credits: 3
Examination process: winter s.:
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Extent per academic year: 60 [hours]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Teaching methods: full-time
Explanation: N. Kutinová Canová
Old code: 386
Guarantor: prof. MUDr. Ondřej Slanař, Ph.D.
Comes under: Compulsory for GM 4.y._24/25
Attributes: Lékařství
Teoretický předmět
Pre-requisite : B83164
Is pre-requisite for: B80306, B80124, B81607, B82424, B80120, B80760, B83007, B80410, B80304, B80305, B80579, B80307, B80602, B80084, B83304, B80302
Annotation
Pharmacology, pharmacodynamics, molecular mechanisms of drug action and drug targets, pharmacokinetics, monitoring drug plasma concentration in relation to therapeutic effects, adverse effects of drugs, system and disease oriented drug groups with pharmacological profiles.
Last update: Kolářová Jana (08.03.2021)
Aim of the course

Knowledge and skills to be acquired: prescription, general knowledge of the basic principles of pharmacology - pharmacokinetics, pharmacodynamics. Special knowledge of basic principles of pharmacology - knowledge of the groups of drugs according to anatomical systems and their diseases, including clinical indications and adverse effects.

Last update: MAT89030 (15.10.2012)
Literature - Czech

Povinná:

  • Katzung, Bertram G. Kruidering-Hall, Marieke Tuan, Rupa Lalchandani Vanderah, Todd W. Trevor, Anthony J.. Katzung & Trevor's pharmacology : examination & board review. New York: McGraw-Hill, 2021, 600 s. ISBN 978-1-260-11712-7.
  • Ritter, James Flower, R. J. Henderson, Graeme Loke, Yoon Kong MacEwan, David J. Robinson, Emma S. J., Fullerton, James. Rang & Dale's pharmacology. London: Elsevier, 2024, 850 s. ISBN 978-0-323-87395-6.
  • Brunton, Laurence L. Knollmann, Björn C. (eds.). Goodman & Gilman's the pharmacological basis of therapeutics. New York: McGraw Hill, 2023, 1645 s. ISBN 978-1-264-25807-9.

Doporučená:

  • Karen Whalen. Lippincott® Illustrated Reviews: Pharmacology, 8th Edition. Philadelphia, US: Lippincott Williams & Wilkins, 2021, 704 s. ISBN 9781975170554.
  • Lüllmann, Heinz, Mohr, Klaus, Hein, Lutz. Color atlas of pharmacology. Stuttgart ; New York: Thieme, 2018, 444 s. ISBN 978-3-13-241065-7.

Last update: Canová Nikolina, MUDr., Ph.D. (13.09.2024)
Teaching methods

Pharmacology 2 B80386

Organization of teaching the master's form of General medicine + Erasmus study at the Institute of Pharmacology of the 1st Medical Faculty of Charles University for the winter semester 2024/2025:

Teaching takes place in the form of lectures and seminars according to the schedule published in the SIS. Attendance at lectures is recommended, attendance at seminars is mandatory.

An exceptions are the first three teaching weeks, when compulsory presence lectures take place (seminars do not take place). Plese, follow "Schedule" in the SIS.

 

Schedule of group seminars, teachers, and lecture rooms in the Institute of Pharmacology, 1st Faculty of Medicine, Charles University in Prague, Albertov 4, Prague 2:

 

Tuesdays 13.00 - 14.30 (since 22.10.2024):

4051: PharmDr. Hartinger, Ph.D. + MUDr. Hronová, Ph.D.  – seminar room: No. 3 (door No. 1133, ground floor)

4052 + Erasmus: Mgr. Michaličková, Ph.D.  - seminar room: No. 2 (door No. 2080, 1st floor)

Wednesdays 14.45 - 16.15 (since 23.10.2024):

4053: MUDr. Canová, Ph.D. – seminar room: No. 3 (door No. 1133, ground floor)

4054: PharmDr. Merdita - seminar room: No. 2 (door No. 2080, 1st floor)

Thursdays 13.00 - 14.30 - Lectures in the lecture hall of the Institute of Pharmacology (since 24 10. 2024)

  

If you have any questions, do not hesitate to contact us.

MUDr. Nikolina Canová, Ph.D. (ncano@lf1.cuni.cz ), representative for teaching 

prof. MUDr. Ondřej Slanař, Ph.D. (oslan@lf1.cuni.cz ), head of the department

Last update: Canová Nikolina, MUDr., Ph.D. (13.09.2024)
Syllabus

Topics of lectures and seminars:

• Antihypertensives, pharmacotherapy of hypertension

• Antiobesity drugs

• Medicines that affect blood clotting

• Hypolipidemics

• Antiarrhythmics

• Antivirals

• Antibiotics

• Antidiabetics, insulins

• Pharmacotherapy of thyroid disorders

• Treatment of osteoporosis

• Immunopharmacology

• Cell and gene therapy, biological treatment

• Anticancer pharmacotherapy

• Remedies for respiratory diseases

• Pharmacotherapy of acute conditions

• Pharmacotherapy of pregnant women, lactating women, children and the elderly

• Drugs for diseases of the urogenital tract, drugs used in obstetrics

Last update: Kolářová Jana (08.03.2021)
Education plan -
Schedule semestral
Educational week Date From - To Education type Theme Teacher Files Note Hodnocení
102.10.202414:15 - 16:00lecturePharmacotherapy of ischemic heart disease. Antiarrhythmic drugs. The attendance is obligatory for all students. MUDr. Nikolina Canová, Ph.D.Seminars are canceled, however, the attendance at lectures is obligatory for all students. The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
210.10.202412:30 - 14:15lectureHeart failure. Diuretics. Therapy of hypertension. The attendance is obligatory for all students. MUDr. Pavel Ryšánek, Ph.D.Seminars are canceled, however, the attendance at lectures is obligatory for all students. The lecture is held in the lecture hall of the Institute of Pharmacology (2nd floor), Albertov 4, Prague 2, 128 00
316.10.202414:15 - 16:00lectureAntimicrobials I., II. The attendance is obligatory for all students. MUDr. Olga Bartošová, Ph.D.Seminars are canceled, however, the attendance at lectures is obligatory for all students. The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
422.10.202413:00 - 14:30seminarPharmacotherapy of bacterial diseases - case reports.Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
23.10.202414:45 - 16:15seminarPharmacotherapy of bacterial diseases - case reports.Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054 Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
24.10.202413:00 - 14:30lectureAntivirals, antifungals, antiparasitics.Mgr. Danica Michaličková, Ph.D.Since the 4th week, all lectures will be voluntary and be held in the lecture hall of the Institute of Pharmacology (2nd floor), Albertov 4, Prague 2, 128 00
529.10.202413:00 - 14:30seminarTest on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics). Repetition of pharmacokinetics (calculations - examples).  
30.10.202414:45 - 16:15seminarTest on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics). Repetition of pharmacokinetics (calculations - examples).  
31.10.202413:00 - 14:30lectureAnticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.Mgr. Danica Michaličková, Ph.D. 
605.11.202413:00 - 14:30seminarTDM (therapeutic drug monitoring) - separate schedule.From the 6th teaching week, a special seminar on the topic of therapeutic drug monitoring (TDM) will take place - see a separate schedule, which will be available on the institute's bulletin board no later than September 2024.
06.11.202414:45 - 16:15seminarTDM (therapeutic drug monitoring) - separate schedule.From the 6th teaching week, a special seminar on the topic of therapeutic drug monitoring (TDM) will take place - see a separate schedule, which will be available on the institute's bulletin board no later than September 2024.
07.11.202413:00 - 14:30lectureHypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.MUDr. Nikolina Canová, Ph.D. 
712.11.202413:00 - 14:30seminarHypertension therapy overview + case reports. 
13.11.202414:45 - 16:15seminarHypertension therapy overview + case reports. 
14.11.202413:00 - 14:30lectureOverview of hormones. Corticosteroids. MUDr. Olga Bartošová, Ph.D. 
819.11.202413:00 - 14:30seminarTest - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics). Pharmacotherapy of obesity and thyroid dysfunction.  
20.11.202414:45 - 16:15seminarTest - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics). Pharmacotherapy of obesity and thyroid dysfunction.  
21.11.202413:00 - 14:30lectureDrugs used in diseases of the respiratory system.Mgr. Danica Michaličková, Ph.D. 
926.11.202413:00 - 14:30seminarDrugs affecting homeostasis of calcium and other minerals. Pharmacotherapy of osteoporosis.  
27.11.202414:45 - 16:15seminarDrugs affecting homeostasis of calcium and other minerals. Pharmacotherapy of osteoporosis.  
28.11.202413:00 - 14:30lectureDrugs used in diseases of gastrointestinal tract.MUDr. Nikolina Canová, Ph.D. 
1003.12.202413:00 - 14:30seminarPharmacotherapy of respiratory tract system diseases - case reports. 
04.12.202414:45 - 16:15seminarPharmacotherapy of respiratory tract system diseases - case reports. 
05.12.202413:00 - 14:30lectureDrugs used to treat diseases of the urogenital tract, drugs used in obstetrics.MUDr. Olga Bartošová, Ph.D. 
1110.12.202413:00 - 14:30seminarTest - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases). Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).  
11.12.202414:45 - 16:15seminarTest - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases). Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).  
12.12.202413:00 - 14:30lecturePharmacotherapy of anemia. Blood, plasma, blood substitutes, blood derivatives. Parenteral nutrition.MUDr. Karolína Hronová, Ph.D. 
1217.12.202413:00 - 14:30seminarPharmacotherapy of acute conditions – case studies. 
18.12.202414:45 - 16:15seminarPharmacotherapy of acute conditions – case studies. 
19.12.202413:00 - 14:30lectureCell and gene therapy, biological treatment. Immunopharmacologyprof. MUDr. Ondřej Slanař, Ph.D. 
1307.01.202513:00 - 14:30seminarPharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout. 
08.01.202514:45 - 16:15seminarPharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout. 
09.01.202513:00 - 14:30lecturePharmacotherapy in pregnant women, breastfeeding, children and the elderly.MUDr. Karolína Hronová, Ph.D. 
1414.01.202513:00 - 14:30seminarRepetition of psychotropic drugs.  
15.01.202514:45 - 16:15seminarRepetition of psychotropic drugs.  
16.01.202513:00 - 14:30lectureDrugs in palliative therapyMUDr. Olga Bartošová, Ph.D. 
1521.01.202513:00 - 14:30seminarTest - psychotropic drugs. Repetition of prescription writing. CREDIT 
22.01.202514:45 - 16:15seminarTest - psychotropic drugs. Repetition of prescription writing. CREDIT 
23.01.202513:00 - 14:30lectureAcute and chronic drug intoxication – treatment and antidotes.prof. MUDr. Ondřej Slanař, Ph.D. 
 
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