Clinical case studies from all medical fields with an emphasis on laboratory tests results. The aim of the subject is
to practice the indication and interpretation of laboratory tests. Discussions take place and students will be asked
to:
a) establishment of diagnosis,
b) differential diagnosis,
c) suggestion of further investigations,
d) suggestion of therapy.
Last update: Kolářová Jana (05.03.2021)
Literature
Obligatory:
Gaw, Allan. Clinical biochemistry : an illustrated colour text. Edinburgh: Churchill Livingstone/Elsevier, 2013, 187 s. ISBN 978-0-7020-5179-1.
Rifai, Nader, Horvath, Andrea R. Wittwer, C. (eds.). Clinical chemistry and molecular diagnostics. : Elsevier Books, 2018, 1867 s. ISBN 978-0-323-35921-4.
BHAGAVAN, N. V. Essentials of Medical Biochemistry With Clinical Cases: Second Edition. : Elsevier, 2015, 752 s. ISBN 0124166873.
WILLIAMSON, MARY A., SNYDER, L. MICHAEL. Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (Interpretation of Diagnostric Tests). : Wolters Kluwer, 2015, 1288 s. ISBN 978-1451191769.
FISCHBACH, FRANCES T., FISCHBACH, MARGARET, A. Fischbach's A Manual of Laboratory and Diagnostic Tests. : Wolters Kluwer, 2017, 1224 s. ISBN 978-1496377128.
Last update: Šebesta Ivan, MUDr., CSc. (13.09.2023)
Requirements to the exam
Information for students of study groups: 5051,5052
- teaching starts on Monday 2nd October 2023 at 8,00 a.m.
- at Kateřinská 32, Inst Med Biochem Lab Dg (ÚLBLD) ground floor, room No. 1.089.
Questions Clinical biochemistry , 5th year, foreign students :
Proteins in plasma, albumin, total protein Sodium, potassium, chloride, calcium, phosphate, magnesium Water homeostasis, effective osmolality and its disorders
Acid base balance
Monitoring scope in the intensive care
Glucose in blood and urine, ketone bodies, lactate Tests for diabetes mellitus (oGTT,insulin,C-peptide,GAD Ab,HbA1,AGE and others) Urinalysis, examination of the urinary sediment Investigation of the lipid disorders Assessment of the antioxidants capacity, acute - phase reactants
Iron, transferrin, ferritin
Investigations of the impairment of the hepatocytes
Investigation of the porphyrias
Investigation of the small intestine, function tests in gastroenterology Screening tests in gastroenterology
Examination in endocrinology Tumor markers Trace elements Investigation of cerebrospinal fluid
Preanalytical variables, preparing of the patient, collection of the specimen
Biological influences on the laboratory results
Point of care testing, dry chemistry
Urgent tests Basic principles of the laboratory techniques, photometry, chromatography, ELISA
Therapeutic drug monitoring, drug screening
Investigation and dif.dg. of the bone diseases
Differential diagnosis of hyperbilirubinaemia and jaundice Dif.dg. of acute heart diseases
Metabolic syndrome, dif.dg. of hyper and hypouricaemia Dif.dg. of pancreas impairment Assessment of renal function, dif.dg. of renal failure
Dif.dg. of proteinuria
Investigation and dif.dg. of urolithiasis Screening of congenital defects Inborn errors of metabolism, basic indications for investigation, phenylketonuria Cytogenetic analysis and its meaning in different clinical specialities Laboratory control of anticoagulants treatment
Anemias
Preparation of samples for direct detection of infectious agens
Basic principles of proper use of antibiotics
Last update: Šebesta Ivan, MUDr., CSc. (13.09.2023)
Education plan -
Schedule block
Week of the block
Day
From - To
Education type
Theme
Teacher
Files
Note
Hodnocení
4
Monday
08:00 - 09:15
seminar
Toxicology,therapeutic drug monitoring
doc. Ing. Drahomíra Springer, Ph.D.
průměr: 5, hodnoceno: 2x
09:25 - 11:20
seminar
Organization of teaching (exam terms).
The impact of preanalytical variables on quality of laboratory results.Indication and interpretation of laboratory tests. POCT. Metabolic disorders.
MUDr. Ivan Šebesta, CSc.
The seminars will take place at lecture hall of Inst Med Bioch Lab Dg,Kateřinská 32, (Dean´s office building,ground floor,door No.1.089) on : 30st OSEptember- 4th October 2024 (1st week of teaching) for study groups 5051+5052; 14th - 18th October 2024 for 5053+5054 .
Clinical case studies with emphasis on laboratory tests results will be presented. Students will be asked for a ) establishment of diagnosis, b) differential diagnosis, c) suggestion of further investigations , d) suggestion of therapy
průměr: 5, hodnoceno: 3x
11:30 - 13:00
seminar
Tumor markers.
Interpretation of results with psychosomatic overlap.
prof. MUDr. Marta Kalousová, Ph.D.
Tuesday
08:00 - 09:00
seminar
Cerebrospinal fluid
prof. MUDr. Marta Kalousová, Ph.D.
09:05 - 10:30
seminar
Inborn errors of metabolism.
doc. RNDr. MUDr. Pavel Ješina, Ph.D.
průměr: 5, hodnoceno: 1x
10:35 - 13:00
seminar
Gastroenterology
MUDr. Petr Kocna, CSc.
Wednesday
08:00 - 09:45
seminar
Hepatology.
prof. MUDr. Libor Vítek, Ph.D.
09:50 - 11:15
seminar
Hematology.
doc. MUDr. Tomáš Kvasnička, CSc.
11:20 - 13:00
seminar
Diabetes mellitus,Endocrinology,osteology
MUDr. Zdislava Vaníčková
Thursday
08:00 - 10:00
seminar
Acid base balance.Hydration,osmolality.
The teacher is: Svobodova,MD
10:15 - 12:00
seminar
Monitoring scope in the intensive care.
doc. MUDr. Helena Lahoda Brodská, Ph.D.
12:05 - 13:00
seminar
Microbiology.
The teacher is: MUDr.Adámková,Ph.D.
Friday
08:00 - 09:00
seminar
Screening of inborn defects.
doc. Ing. Drahomíra Springer, Ph.D.
09:15 - 10:15
seminar
Classical and oncological genetics.
The teacher is : RNDr.Lizcová,Ph.D.
10:30 - 12:15
seminar
Nephrology,inflammation,oxidative stress.
prof. MUDr. Tomáš Zima, DrSc., MBA
This seminar also teaches: prof.MUDr.M.Kalousová,Ph.D.
Course-unit credit - Dr.I.Šebesta,Ph.D.
Rozpis blokový
Týden bloku
Den
Od - Do
Typ výuky
Téma
Učitel
Soubory
Poznámka
Hodnocení
4
Pondělí
08:00 - 09:15
seminář
Toxicology,therapeutic drug monitoring
doc. Ing. Drahomíra Springer, Ph.D.
průměr: 5, hodnoceno: 2x
09:25 - 11:20
seminář
Organization of teaching (exam terms).
The impact of preanalytical variables on quality of laboratory results.Indication and interpretation of laboratory tests. POCT. Metabolic disorders.
MUDr. Ivan Šebesta, CSc.
The seminars will take place at lecture hall of Inst Med Bioch Lab Dg,Kateřinská 32, (Dean´s office building,ground floor,door No.1.089) on : 30st OSEptember- 4th October 2024 (1st week of teaching) for study groups 5051+5052; 14th - 18th October 2024 for 5053+5054 .
Clinical case studies with emphasis on laboratory tests results will be presented. Students will be asked for a ) establishment of diagnosis, b) differential diagnosis, c) suggestion of further investigations , d) suggestion of therapy
průměr: 5, hodnoceno: 3x
11:30 - 13:00
seminář
Tumor markers.
Interpretation of results with psychosomatic overlap.
prof. MUDr. Marta Kalousová, Ph.D.
Úterý
08:00 - 09:00
seminář
Cerebrospinal fluid
prof. MUDr. Marta Kalousová, Ph.D.
09:05 - 10:30
seminář
Inborn errors of metabolism.
doc. RNDr. MUDr. Pavel Ješina, Ph.D.
průměr: 5, hodnoceno: 1x
10:35 - 13:00
seminář
Gastroenterology
MUDr. Petr Kocna, CSc.
Středa
08:00 - 09:45
seminář
Hepatology.
prof. MUDr. Libor Vítek, Ph.D.
09:50 - 11:15
seminář
Hematology.
doc. MUDr. Tomáš Kvasnička, CSc.
11:20 - 13:00
seminář
Diabetes mellitus,Endocrinology,osteology
MUDr. Zdislava Vaníčková
Čtvrtek
08:00 - 10:00
seminář
Acid base balance.Hydration,osmolality.
The teacher is: Svobodova,MD
10:15 - 12:00
seminář
Monitoring scope in the intensive care.
doc. MUDr. Helena Lahoda Brodská, Ph.D.
12:05 - 13:00
seminář
Microbiology.
The teacher is: MUDr.Adámková,Ph.D.
Pátek
08:00 - 09:00
seminář
Screening of inborn defects.
doc. Ing. Drahomíra Springer, Ph.D.
09:15 - 10:15
seminář
Classical and oncological genetics.
The teacher is : RNDr.Lizcová,Ph.D.
10:30 - 12:15
seminář
Nephrology,inflammation,oxidative stress.
prof. MUDr. Tomáš Zima, DrSc., MBA
This seminar also teaches: prof.MUDr.M.Kalousová,Ph.D.
Course-unit credit - Dr.I.Šebesta,Ph.D.