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| Order | Course title |
| Topic 1 (TO1) | |
| 1 | a Bronchial asthma b Non-Hodgkin lymphoma, chronic lymphocytic leukemia, and related diseases c Differential diagnosis of edema |
| 2 | a Thrombophilic disorders, anticoagulation treatment b Pleural diseases c Differential diagnosis of renal insufficiency |
| 3 | a Viral hepatitis b Metabolic osteopathy c Differential diagnosis of chest pain |
| 4 | a Endocarditis b Gouty arthritis c Differential diagnosis of dyspnea |
| 5 | a Type 2 diabetes mellitus b Principles of supportive care in hematology; febrile neutropenia c Differential diagnosis of pleural effusion |
| 6 | a Shock states b Reactive and psoriatic arthritis c Differential diagnosis of dysphagia |
| 7 | a Diseases of the stomach and duodenum b Principles of effective hemotherapy; transfusion products and blood derivatives. Prerequisites for blood donation, donor examination. Hemapheresis in clinical hematology and transfusion medicine; principles of immunohematology c Differential diagnosis of hematuria |
| 8 | a Diseases of the large intestine b Lung diseases in systemic connective tissue diseases and vasculitis c Differential diagnosis of pathological laboratory findings of blood count (red and white blood cells and thrombocytes) |
| 9 | a Arterial hypertension b Interstitial pneumonia caused by exogenous causes c Differential diagnosis of anorexia and weight loss |
| 10 | a Hypofunction and hyperfunction of the thyroid gland b Epidemiology and prevention of cardiovascular disease c Differential diagnosis of abdominal pain |
| 11 | a Diseases of the gallbladder, bile ducts, and jaundice b Systemic vasculitis c Differential diagnosis of lymph node enlargement |
| 12 | a Diseases of the esophagus b Bradycardia c Differential diagnosis of joint pain and swelling |
| 13 | a Acute renal failure b Tachycardia c Differential diagnosis of enterorrhagia and melena |
| 14 | a Liver diseases b Defects of the mitral valve c Differential diagnosis of febrile states |
| 15 | a Defects of the aortic valve b Myeloproliferative diseases - CML (chronic myeloid leukemia) and Ph negative myeloproliferation c Differential diagnosis of ascites |
| 16 | a Heart failure b Gonadal diseases, polyglandular syndromes c Differential diagnosis of high erythrocyte sedimentation rate (ESR) and CRP |
| 17 | a Cardiopulmonary resuscitation b Monoclonal gammopathy; plasmacytoma; amyloidosis c Differential diagnosis of jaundice |
| 18 | a Lung cancer b Defects of the right heart, congenital heart defects c Differential diagnosis of hyponatremia |
| 19 | a Diseases of the pancreas b Osteoarthritis and spondylarthritis c Differential diagnosis of obesity |
| 20 | a Pneumonia, lung abscess, bronchiectasis b Gastrointestinal tract bleeding c Differential diagnosis of syncope |
| 21 | a Chronic obstructive pulmonary disease b Deep vein thrombosis and pulmonary embolism c Differential diagnosis of eating disorders |
| 22 | a Diseases of the peripheral arteries and veins b Complications of liver cirrhosis c Differential diagnosis of muscle pain |
| 23 | a Stroke b Idiopathic pulmonary fibrosis c Differential diagnosis of nephrotic syndrome |
| 24 | a Chronic forms of coronary heart disease b Congenital kidney diseases c Differential diagnosis of peripheral cytopenia |
| 25 | a Acute coronary syndromes b Ankylosing spondylitis c Differential diagnosis of hypokalemia and hyperkalemia |
| 26 | a Diseases of the small intestine b Endocrine arterial hypertension c Differential diagnosis of chronic fatigue |
| 27 | a Tuberculosis b Diseases of the adrenal glands c Differential diagnosis of hypoglycemia and hyperglycemia |
| 28 | a Chronic renal failure b Myocarditis, pericardial diseases c Differential diagnosis of pathological biochemical laboratory findings (minerals, renal parameters, proteins) |
| 29 | a Aortic diseases b Diseases of the pituitary gland and hypothalamus c Differential diagnosis of anemia (hemolytic vs hypoproliferative anemias) |
| 30 | a Type 1 diabetes mellitus b Functional disorders of the GI tract c Differential diagnosis of disorders of consciousness |
| 31 | a Colorectal cancer b Glomerulopathies in systemic diseases (diabetes, ANCA vasculitis, antiGBM, myeloma) c Differential diagnosis of nausea and vomiting |
| 32 | a Acute leukemia, bone marrow suppression, myelodysplastic syndrome b Smoking c Differential diagnosis of oliguria and anuria |
| 33 | a Hodgkin`s lymphoma; diff. dg. of lymfadenomegaly and splenomegaly b Hyponatremia and hypernatremia, changes in water content in the body c Differential diagnosis of osteoporosis |
| 34 | a Respiratory insufficiency b Disorders of phospho-calcium metabolism, diseases of the parathyroid glands c Differential diagnosis of bleeding into body cavities |
| 35 | a Disorders of plasma lipid metabolism - dyslipidemia b Tubulointerstitial nephritis c Differential diagnosis of hemoptysis |
| 36 | a Obesity b Rheumatoid arthritis and juvenile idiopathic arthritis c Differential diagnosis of cough |
| 37 | a Pulmonary hypertension b Eating disorders c Differential diagnosis of pathological liver tests |
| 38 | a Hemolytic anemias (e.g. AIHA, spherocytic, MAHA…) Hypoproliferative anemias. (e.g.Iron deficiency, megaloblastic and anemia of chronic diseases…) b Systemic scleroderma, polymyositis, dermatomyositis, Sjögren's syndrome c Differential diagnosis of hematemesis |
| 39 | a Glomerulonephritis b Metabolic syndrome and cardiometabolic risk c Differential diagnosis of hepatomegaly and splenomegaly |
| 40 | a Bleeding disorders; thrombocytopenia, thrombocytopathy, disseminated intravascular coagulation syndrome b Nodes, tumors, and inflammation of the thyroid gland c Differential diagnosis of nausea and vomiting |
| 41 | a Diseases of the mediastinum b Extra-articular rheumatism c Differential diagnosis of abdominal pain |
| 42 | a Emergencies in pneumology b Systemic lupus erythematosus c Differential diagnosis of anorexia and weight loss |
| 43 | a Sarcoidosis b Risk factors of cardiovascular diseases and determination of CV risk c Differential diagnosis of chest pain |
| 44 | a Respiratory disorders in sleep b Cardiomyopathy c Differential diagnosis of oliguria and anuria |
| 110 | Protocol on Practical part for Internal Medicine State Examination Excellent Very good Good |
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Klener P et al: Vnitřní lékařství. Galén Praha 2011 Last update: KAR04325 (14.11.2011)
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New questions for the state rigorous examination in internal medicine published on the 1st December 2020 below, will be valid for the state rigorous examination from the beginning of the academic year 2021/2022. Their full wording is published on the websites of individual departments guaranteeing SRE and, also, in the SIS. The questions consist of three sub-questions. Sub-questions a) and b) correspond to two thematic areas, each representing two subfields of internal medicine. The third sub-question c) is focused on the differential diagnosis. If the answer to one of the sub-questions a) to c) is classified as failed, then the entire SRE is classified as failed. If the classification for sub-question a) or b) is failed, SRE ends and the student will not answer other sub-questions that have not yet been answered.
1. a) Bronchial asthma b) Non-Hodgkin lymphoma, chronic lymphocytic leukemia, and related diseases c) Differential diagnosis of edema
2. a) Thrombophilic disorders, anticoagulation treatment b) Pleural diseases c) Differential diagnosis of renal insufficiency
3. a) Viral hepatitis b) Metabolic osteopathy c) Differential diagnosis of chest pain
4. a) Endocarditis b) Gouty arthritis c) Differential diagnosis of dyspnea
5. a) Type 2 diabetes mellitus b) Principles of supportive care in hematology; febrile neutropenia c) Differential diagnosis of pleural effusion
6. a) Shock states b) Reactive and psoriatic arthritis c) Differential diagnosis of dysphagia
7. a) Diseases of the stomach and duodenum b) Principles of effective hemotherapy; transfusion products and blood derivatives. Prerequisites for blood donation, donor examination. Hemapheresis in clinical hematology and transfusion medicine; principles of immunohematology c) Differential diagnosis of hematuria
8. a) Diseases of the large intestine b) Lung diseases in systemic connective tissue diseases and vasculitis c) Differential diagnosis of pathological laboratory findings of blood count (red and white blood cells and thrombocytes)
9. a) Arterial hypertension b) Interstitial pneumonia caused by exogenous causes c) Differential diagnosis of anorexia and weight loss
10. a) Hypofunction and hyperfunction of the thyroid gland b) Epidemiology and prevention of cardiovascular disease c) Differential diagnosis of abdominal pain
11. a) Diseases of the gallbladder, bile ducts, and jaundice b) Systemic vasculitis c) Differential diagnosis of lymph node enlargement
12. a) Diseases of the esophagus b) Bradycardia c) Differential diagnosis of joint pain and swelling
a) Acute renal failure b) Tachycardia c) Differential diagnosis of enterorrhagia and melena
14. a) Liver diseases b) Defects of the mitral valve c) Differential diagnosis of febrile states
15. a) Defects of the aortic valve b) Myeloproliferative diseases - CML (chronic myeloid leukemia) and Ph negative myeloproliferation c) Differential diagnosis of ascites
16. a) Heart failure b) Gonadal diseases, polyglandular syndromes c) Differential diagnosis of high erythrocyte sedimentation rate (ESR) and CRP
17. a) Cardiopulmonary resuscitation b) Monoclonal gammopathy; plasmacytoma; amyloidosis c) Differential diagnosis of jaundice
18. a) Lung cancer b) Defects of the right heart, congenital heart defects c) Differential diagnosis of hyponatremia
19. a) Diseases of the pancreas b) Osteoarthritis and spondylarthritis c) Differential diagnosis of obesity
20. a) Pneumonia, lung abscess, bronchiectasis b) Gastrointestinal tract bleeding c) Differential diagnosis of syncope
21. a) Chronic obstructive pulmonary disease b) Deep vein thrombosis and pulmonary embolism c) Differential diagnosis of eating disorders
22. a) Diseases of the peripheral arteries and veins b) Complications of liver cirrhosis c) Differential diagnosis of muscle pain
23. a) Stroke b) Idiopathic pulmonary fibrosis c) Differential diagnosis of nephrotic syndrome
24. a) Chronic forms of coronary heart disease b) Congenital kidney diseases c) Differential diagnosis of peripheral cytopenia
25. a) Acute coronary syndromes b) Ankylosing spondylitis c) Differential diagnosis of hypokalemia and hyperkalemia
a) Diseases of the small intestine b) Endocrine arterial hypertension c) Differential diagnosis of chronic fatigue
27. a) Tuberculosis b) Diseases of the adrenal glands c) Differential diagnosis of hypoglycemia and hyperglycemia
28. a) Chronic renal failure b) Myocarditis, pericardial diseases c) Differential diagnosis of pathological biochemical laboratory findings (minerals, renal parameters, proteins)
29. a) Aortic diseases b) Diseases of the pituitary gland and hypothalamus c) Differential diagnosis of anemia (hemolytic vs hypoproliferative anemias)
30. a) Type 1 diabetes mellitus b) Functional disorders of the GI tract c) Differential diagnosis of disorders of consciousness
31. a) Colorectal cancer b) Glomerulopathies in systemic diseases (diabetes, ANCA vasculitis, antiGBM, myeloma) c) Differential diagnosis of nausea and vomiting
32. a) Acute leukemia, bone marrow suppression, myelodysplastic syndrome b) Smoking c) Differential diagnosis of oliguria and anuria
33. a) Hodgkin`s lymphoma; diff. dg. of lymfadenomegaly and splenomegaly b) Hyponatremia and hypernatremia, changes in water content in the body c) Differential diagnosis of osteoporosis
34. a) Respiratory insufficiency b) Disorders of phospho-calcium metabolism, diseases of the parathyroid glands c) Differential diagnosis of bleeding into body cavities
35. a) Disorders of plasma lipid metabolism - dyslipidemia b) Tubulointerstitial nephritis c) Differential diagnosis of hemoptysis
36. a) Obesity b) Rheumatoid arthritis and juvenile idiopathic arthritis c) Differential diagnosis of cough
37. a) Pulmonary hypertension b) Eating disorders c) Differential diagnosis of pathological liver tests
38. a) Hemolytic anemias (e.g. AIHA, spherocytic, MAHA…) Hypoproliferative anemias. (e.g.Iron deficiency, megaloblastic and anemia of chronic diseases…) b) Systemic scleroderma, polymyositis, dermatomyositis, Sjögren's syndrome c) Differential diagnosis of hematemesis
39. a) Glomerulonephritis b) Metabolic syndrome and cardiometabolic risk c) Differential diagnosis of hepatomegaly and splenomegaly
40. a) Bleeding disorders; thrombocytopenia, thrombocytopathy, disseminated intravascular coagulation syndrome b) Nodes, tumors, and inflammation of the thyroid gland c) Differential diagnosis of nausea and vomiting
41. a) Diseases of the mediastinum b) Extra-articular rheumatism c) Differential diagnosis of abdominal pain
42. a) Emergencies in pneumology b) Systemic lupus erythematosus c) Differential diagnosis of anorexia and weight loss
43. a) Sarcoidosis b) Risk factors of cardiovascular diseases and determination of CV risk c) Differential diagnosis of chest pain
44. a) Respiratory disorders in sleep b) Cardiomyopathy c) Differential diagnosis of oliguria and anuria Last update: Kohútová Vladislava, Ing. (17.03.2021)
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