Clinical Genetics - F0109170

• Title: Klinická genetika
• Guaranteed by: Department of Medical Genetics (15-610)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2008
• Semester: winter
• Points: 0
• E-Credits: 2
• Examination process: winter s.:
• Hours per week, examination: winter s.:0/30, C [HS]
• Capacity: 30
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: cancelled
• Language: Czech
• Teaching methods: full-time
• Teaching methods: full-time
• Additional information: http://CGEM1ECM
• Note: course can be enrolled in outside the study plan
• Guarantor: MUDr. Věra Jüttnerová
• Pre-requisite : {Maláskup. BiII}
• Is incompatible with: FV50016, FV072
• Is interchangeable with: FV50016, FV072

Annotation

English

Last update: ZALUDOVA (30.07.2003)

Structure and function of gene, direct, indirect DNA analysis of diseases. PCR. Chromosome aberrations, clinical cytogenetics. Mendelian inheritance. Multifaktorial inheritance. Pedigree analysis. Genetic risk and prognosis. Dysmorfology. Teratogenic agents, risk for pregnancy. Syndromology. Prenatal diagnosis of inborn errors, genetic diseases. Screening tests. Genetic prevention. Ethical aspects of genetic counseling. Single gene determination of cancer. Multifactorial predisposition of cancer. Molecular oncogenesis.

Czech

Last update: ZALUDOVA (30.07.2003)

Struktura a funkce genu, přímá a nepřímá DNA analýza chorob, PCR. Chro-mozomální aberace, klinická cytogenetika. Monogenní dědičnost. Multifakto-riální dědičnost. Rodokmenová analýza. Genetické riziko a prognosa. Dys-morfologie. Teratogeny, riziko v graviditě. Syndromologická diagnostika. Pre-natální diagnostika. Screeningové testy. Možnosti genetické prevence. Etické a právní aspekty genetické konzultace. Monogenní determinace malignity. Multifaktoriální predisposice k malignitě. Molekulární onkogeneze.