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Last update: RNDr. Hana Španielová, Ph.D. (17.04.2023)
These lectures focus on a comparative analysis of key mechanisms of carcinogenesis and viral tumorigenesis. Using examples of well-studied cases of virus-induced tumors, it attempts to offer parallels for understanding the molecular, cellular, and immunological mechanisms that play a role in carcinogenesis in general and may be important for identifying therapeutic targets. The presentation also introduces modern strategies for targeted anticancer therapy, with emphasis on approaches where viruses can be used as anticancer vaccines or vectors to deliver genes, therapeutics or diagnostic agents into cancer cells. This course provides an up-to-date overview of cancer virotherapy and oncolytic viruses. This course is designed for students interested in molecular and cell biology, virology and oncology. During the course, students will be given the opportunity to work individually with scientific literature related to cancer biology and possibly test their argumentation skills in a panel discussion on a chosen controversial topic. |
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Last update: RNDr. Hana Španielová, Ph.D. (04.05.2023)
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Last update: RNDr. Hana Španielová, Ph.D. (04.05.2023)
Requirements - the exam is combined and has three parts: 1. During the semester, submission of an independent paper in an agreed form and date = 20% evaluation. 2. Passing a short test with at least 70% success before the exam = 30% evaluation 3. Oral examination = 50% evaluation |