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Last update: doc. RNDr. Ivan Jelínek, CSc. (25.10.2019)
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Last update: doc. RNDr. Ivan Jelínek, CSc. (25.10.2019)
Spektrometrické analytické metody II., I. Němcová, P. Engst, I. Jelínek, J. Sejbal, P. Rychlovský, Karolinum, Praha 1998 (Lecture notes). On-line data are not available. |
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Last update: doc. RNDr. Ivan Jelínek, CSc. (25.10.2019)
Exam rules Taking the written test covering lectured problematics. |
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Last update: doc. RNDr. Ivan Jelínek, CSc. (25.10.2019)
Introduction. Experimental setup of mass spectrometer. The survey of ionization techniques. Mass analyzers. Magnetic sector. Electric sector. Quadrupole mass analyzer. Ion trap. Time of flight mass analyzer. Detectors. Multiplier detectors. Scintillation photomultiplier detectors. Mass spectrum. Molecular ion. Analysis of isotopic composition. Stable isotopes. Ring + double bonds rule. Theory of fragmentation. Charge and unpaired electron localization in molecular ion. Fragmentation of molecular ions, fragmentation pathways. Factors influencing ion intensity. Fragmentation mechanisms of organic molecules. Sigma bond cleavage. Alpha cleavage initiated by radical site. Cleavage initiated charge site. Cleavage of cyclic structures. Rearrangement reactions. Rearrangements initiated by radical site. Rearrangements initiated by charge site. Mass spectra of simple organic compounds and their interpretation. |