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Last update: Ing. Dušan Drahoňovský, Ph.D. (18.02.2013)
Nomenclature of organic compounds (main chain, group, locants, prefixes and suffixes) . Spatial structures of organic compounds, double bond isomers, chirality, enantiomers and diastereomeric compounds. Configuration and conformation, relationships. Lewis structures, formal charges, acidity, hard and soft acids and bases. Resonance, aromaticity, classification of substituents, reactivity of polycyclic arenes. Intermediates: carbocations, carbanions, carbenes, radicals - electronic structure. |
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Last update: Mgr. Michal Urban, Ph.D. (01.12.2023)
John McMurry: Organická chemie, 2015 (v češtině) nebo též anglické vydání. Susan McMurry: Studijní příručka a řešené příklady k českému vydání učebnice "John McMurry: Organická chemie", 2004 Další literatura: Organic Chemistry (Clayden, Greeves, Warren), second edition, 2012 Sacharidy (Černý, Trnka, Buděšínský), 2 vydání, 2016 |
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Last update: Mgr. Michal Urban, Ph.D. (25.01.2024)
Organická chemie I(b) je zakončena zápočtem a zkouškou; podmínky se řídí zkušebním řádem PřF UK. Zápočet: Pro úspěšné získání zápočtu se požaduje:
. Zkouška: Je písemná a je podmíněna zápočtem. Rovněž je nutný zisk alespoň 60% bodů ze zkouškového testu. |
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Last update: RENA (16.06.2003)
Structure of organic compounds, properties of covalent bond, reactions on covalent bonds. Nomenclature of organic compounds (main chain, group, locants, prefixes and suffixes) . Spatial structures of organic compounds, double bond isomers, chirality, enantiomers and diastereomeric compounds. Configuration and conformation, relationships. Lewis structures, formal charges, acidity, hard and soft acids and bases. Resonance, aromaticity, classification of substituents, reactivity of polycyclic arenes. Intermediates: carbocations, carbanions, carbenes, radicals - electronic structure. Electronic and steric effects on the stability of molecules and intermediates. Mechanism of reactions: radical, nucleophilic and electrophilic substitution, radical and electrophilic addition, synchronous addition, cis- and trans- elimination. Conversion of functional groups - main types of functional groups and their interconversion - substitution, addition, oxidation and reduction. Skeleton building reactions (aldol, Grignard, malonester, cyanohydrine and so on). Interesting rearrangements, photochemistry, enzymatic reactions. The planning of organic synthesis, retrosynthetic approach. Relationship between structure of compounds and physicochemical properties and biological activity. |