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Last update: Mgr. Marian Novotný, Ph.D. (30.09.2021)
We will deal with: a) the basics of modelling and simulations, including various approaches (especially from the point of view of the compartments and their interactions), including suitable and appropriate mathematical background b) application of models to specific biological situations - according to articles Students will try and explore: a) a simple continuous compartmental model of immunity and its behavior, including the classification of system developments b) connection of the model with the data c) formulation of the model and its implementation d) a more complex discrete cell model with applications to cell differentiation and chemotactic motion The research is conducted both analytically (what and why is happening) and synthetically (creating a system of given properties). |
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Last update: Mgr. Marian Novotný, Ph.D. (30.09.2021)
Stuart Russell and Peter Norvig; Artificial Intelligence: A Modern Approach; Prentice Hall, 3. edition, (2010) Hiroki Sayama; Introduction to the Modeling and Analysis of Complex Systems; Open SUNY Textbooks, Milne Library, (2015) Seeing around corners: Cells solve mazes and respond at a distance using attractant breakdown, Science 28 Aug 2020: Vol. 369, Issue 6507, eaay9792, DOI: 10.1126/science.aay9792 Mayer H, Zaenker KS, An Der Heiden U. A basic mathematical model of the immune response. Chaos. 1995 Mar; 5:155-161. DOI: 10.1063/1.166098. PMID: 12780168. |
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Last update: Mgr. Marian Novotný, Ph.D. (30.09.2021)
Credit will be awarded for this course by successfully completing the following requirements:
Due to the nature of the requirements, a failed attempt cannot be repeated as is possible for exams. The teacher may establish conditions whereby a student can make up for missing active participation assignments or resubmit their semester project after improving deficiencies that were found the previous time around.
The examination consists of written and oral parts involving the ability to apply the gained knowledge to solve exercises.
The examination could be in the contact or distance form.
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Last update: Mgr. Marian Novotný, Ph.D. (30.09.2021)
Models and Simulations
Simple model of immunity - experiments with a given model
Creation and description of the model
Generalization of interactions
Generalization of models
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