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Last update: prof. RNDr. Jan Veselý, Ph.D. (16.06.2014)
This course is for ERASMUS students also available in English. |
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Last update: prof. RNDr. Jan Veselý, Ph.D. (24.10.2019)
Recommended literature: Elektronic materials (lectures) are also available in SIS.
Other books: Laszlo Kurti, Barbara Czako: Strategic Applications of Named Reactions in Organic Synthesis, Academic Press, 2005, ISBN: 9780124297852. |
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Last update: prof. RNDr. Jan Veselý, Ph.D. (24.10.2019)
Requirements for study control:
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Last update: prof. RNDr. Jan Veselý, Ph.D. (08.02.2022)
Syllabus Organic Synthesis II 1. Cycloaddition reactions - Diels-Alder reaction: regioselectivity and stereoselectivity 2. Cycloaddition reactions - Dipolar cycloaddition: ozonolysis, cycloaddition of azides, diazo compounds, azomethinylides, [2 + 2] -cycloaddition 3. Organolithic, organomagnesium and organozinc compounds - preparation and reactivity 4. Organocuprates and organotin compounds - preparation and use 5. Sigmatropic rearrangements 6. Acids and bases catalyzed by rearrangements 7. Nominal reactions 8. Coupling reactions 9. Protecting groups - protection of alcohols, amines, etc. 10. Retrosynthetic analysis - synthons, synthetic equivalents, C-X disconnection 11. Retrosynthesis - C-C disconnection, multiple C-C disconnections |