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Prstencovité lamely a jejich role ve virové infekci
Thesis title in Czech: | Prstencovité lamely a jejich role ve virové infekci |
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Thesis title in English: | Annulate lamellae and their role in viral infection |
Key words: | prstencovité lamely, pórový komplex, nukleoporin, oocyt, virus, endoplazmatické retikulum |
English key words: | annulate lamellae, pore complex, nucleoporin, oocyte, virus, endoplasmic reticulum |
Academic year of topic announcement: | 2023/2024 |
Thesis type: | Bachelor's thesis |
Thesis language: | čeština |
Department: | Department of Genetics and Microbiology (31-140) |
Supervisor: | Mgr. Kateřina Bruštíková, Ph.D. |
Author: | hidden - assigned and confirmed by the Study Dept. |
Date of registration: | 23.10.2023 |
Date of assignment: | 23.10.2023 |
Confirmed by Study dept. on: | 31.01.2024 |
Date of electronic submission: | 29.04.2024 |
Date of proceeded defence: | 04.06.2024 |
Opponents: | Mgr. Irena Vopálenská, Ph.D. |
Preliminary scope of work |
Prstencovité lamely (Annulate lamelae) jsou méně známé organely skládající se z vrstev membrán odvozených od endoplazmatického retikula obsahujících jaderné pórové komplexy. Bakalářská práce bude rozdělena na dvě stejnocenné části. První část se bude zabývat objevem, strukturou a biogenezí prstencovitých lamel i jejich výskytem a rolí v různých buněčných typech. Druhá část si klade za cíl shrnout veškeré poznatky o výskytu a roli prstencovitých lamel v buňkách infikovaných především různými živočišnými RNA viry a případně i DNA viry. |
Preliminary scope of work in English |
Annulate lamellae are lesser known organelles consisting of layers of membranes derived from the endoplasmic reticulum containing nuclear pore complexes. The bachelor thesis will be divided into two equal parts. The first part will be focused on the discovery, structure and biogenesis of annulate lamellae as well as their occurrence and role in different cell types. The second part aims to summarize all knowledge about the occurrence and role of annulate lamellae in cells infected primarily with various animal RNA viruses and possibly also DNA viruses. |