Mikrojádra a jejich spojitost s vrozenou vnitrobuněčnou imunitou a virovou infekcí

• Thesis title in Czech: Mikrojádra a jejich spojitost s vrozenou vnitrobuněčnou imunitou a virovou infekcí
• Thesis title in English: Micronuclei and their connection with intracellular innate immunity and viral infection
• Key words: mikrojádra, vrozená imunita, molekulární senzory, chromotripse
• English key words: micronuclei, innate immunity, molecular sensors, chromotripsis
• Academic year of topic announcement: 2022/2023
• Thesis type: Bachelor's thesis
• Thesis language: čeština
• Department: Department of Genetics and Microbiology (31-140)
• Supervisor: Mgr. Kateřina Bruštíková, Ph.D.
• Author: Bc. Kateřina Knoblochová - assigned and confirmed by the Study Dept.
• Date of registration: 18.10.2022
• Date of assignment: 19.10.2022
• Confirmed by Study dept. on: 23.01.2023
• Date of electronic submission: 03.05.2023
• Date of proceeded defence: 26.05.2023
• Opponents: RNDr. Hana Španielová, Ph.D.
• Award: Thesis was put forward for an award

Preliminary scope of work

Cílem bakalářské shrnout strukturu, vznik a možné role mikrojader, přičemž největší důraz bude kladen na roli mikrojader ve vrozené vnitrobuněčné imunitě. Pokud budou dostupné zdroje, práce by měla rovněž shrnout informace o roli mikrojeder ve virových infekcích.

Preliminary scope of work in English

The aim of the bachelor thesis is to summarize the structure, origin and possible roles of micronuclei, while the greatest emphasis will be placed on the role of micronuclei in innate immunity. If resources are available, the thesis will also summarize information on the role of micronuclei in viral infections.