hidden - assigned and confirmed by the Study Dept.
Date of registration:
11.11.2021
Date of assignment:
11.11.2021
Confirmed by Study dept. on:
11.11.2021
Date of electronic submission:
03.08.2023
Date of proceeded defence:
08.09.2023
Opponents:
Mgr. Markéta Pelantová
Preliminary scope of work
Pohyb savčích buněk je vnímán v jednoznačné příčinné souvislosti s přestavbami aktomyozinové sítě. Mikrotubuly a střední filamenta však dle nejnovějších poznatků hrají v migraci buněk také klíčovou úlohu. Práce si klade za cíl sumarizovat úlohu středních filament pro pohyb savčích buněk; a to jak v kontextu samotného pohybu buněk, tak také v souvislosti s tvorbou buněčných adhezí během migrace.
Preliminary scope of work in English
Mammalian cell migration is perceived in a clear causal link with rearrangement of an actomyosine network. However, the latest scientific records suggest that microtubules and intermediate filaments also play a key role in the cell migration. This thesis summarizes the role of intermediate filaments in mammalian cell motility - in cell motion per se as well as their role in the formation of cellular adhesions during migration.
- assigned and confirmed by the Study Dept.