Thesis (Selection of subject)

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In vitro selekce aptamerů pro methioninsulfoxid

Thesis title in Czech:	In vitro selekce aptamerů pro methioninsulfoxid
Thesis title in English:	In Vitro Selection of Aptamers for Methionine Sulfoxide
Key words:	In vitro selekce, aptamery, post-translační modifikace, redox rovnováha, methioninsulfoxid
English key words:	In vitro selection, aptamers, post-translational modifications, redox balance, methionine sulfoxide
Academic year of topic announcement:	2020/2021
Thesis type:	diploma thesis
Thesis language:	čeština
Department:	Department of Cell Biology (31-151)
Supervisor:	doc. RNDr. Jiří Míšek, Ph.D.
Author:	hidden - assigned by the advisor, waiting for guarantor's approval
Date of registration:	04.11.2020
Date of assignment:	04.11.2020
Date of electronic submission:	26.04.2022
Date of proceeded defence:	07.06.2022
Opponents:	RNDr. Cyril Bařinka, Ph.D.

Preliminary scope of work

Hlavní náplní práce bude in vitro selekce DNA aptamerů pro methioninsulfoxid a následné studium jejich vazebných vlastností a selektivity. Tyto aptamery budou dále využity pro afinitní značení methioninsulfoxidů v proteinech.