Protein transport across the mitochondrial membranes of the unicellular eukaryotes

• Thesis title in Czech: Import proteinů do mitochondrií jednobuněčných eukaryot.
• Thesis title in English: Protein transport across the mitochondrial membranes of the unicellular eukaryotes
• Key words: mitochondrie, translokázy, transport proteinů, evoluce
• English key words: mitochondria, translocases, protein transport, evolution
• Academic year of topic announcement: 2015/2016
• Thesis type: dissertation
• Thesis language: angličtina
• Department: Department of Parasitology (31-161)
• Supervisor: Mgr. Pavel Doležal, Ph.D.
• Author: hidden - assigned by the advisor
• Date of registration: 19.10.2015
• Date of assignment: 19.10.2015

Preliminary scope of work

This project will focus on the protein transport across the mitochondrial membranes of some unicellular eukaryotes from the group of Excavata as they often carry mitochondria with ancestral bacterial features, which may shed light on the origin and the evolution of the mitochondrial protein transport machines. Project will combine tailored bioinformatics, cell biology and biochemical techniques and live cell microscopy in order to define the molecular apparatus behind the protein transport and the organelle division.

Preliminary scope of work in English

This project will focus on the protein transport across the mitochondrial membranes of some unicellular eukaryotes from the group of Excavata as they often carry mitochondria with ancestral bacterial features, which may shed light on the origin and the evolution of the mitochondrial protein transport machines. Project will combine tailored bioinformatics, cell biology and biochemical techniques and live cell microscopy in order to define the molecular apparatus behind the protein transport and the organelle division.