This project will address molecular and physiological functions of key candidate genes that were repeatedly recruited for adaptation in wild members of the leading plant model Arabidopsis. Leveraging extensive knowledge of natural variation of this system, the successful candidate will focus on the functional characterization of key candidate genes involved in repeated adaptation to exceptionally strong selective pressure, toxic soils called serpentines. By focusing on genes harboring independent mutations, the project aims at uncovering general mechanisms determining which portion of genome evolves in a predictable manner. The successful candidate will address the novel gene alleles function on the molecular and cellular level in a fully interdisciplinary manner, resulting in a unique experimental profile of the candidate.